6QK8

Crystal structure of yeast 14-3-3 protein (Bmh1) from Saccharomyces cerevisiae with the Nha1p (yeast Na+/H+ antiporter) 14-3-3 binding motif Ser481

Summary for 6QK8

Entry DOI	10.2210/pdb6qk8/pdb
Descriptor	Protein BMH1, Na(+)/H(+) antiporter (2 entities in total)
Functional Keywords	14-3-3 protein, bmh, na+/h+ antiporter, nha1p, signaling protein
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	8
Total formula weight	111468.37
Authors	Smidova, A.,Obsil, T.,Obsilova, V. (deposition date: 2019-01-28, release date: 2019-10-02, Last modification date: 2024-01-24)
Primary citation	Smidova, A.,Stankova, K.,Petrvalska, O.,Lazar, J.,Sychrova, H.,Obsil, T.,Zimmermannova, O.,Obsilova, V. The activity of Saccharomyces cerevisiae Na+, K+/H+antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481. Biochim Biophys Acta Mol Cell Res, 1866:118534-118534, 2019 Cited by PubMed: 31446061 DOI: 10.1016/j.bbamcr.2019.118534 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.917 Å)

Structure validation