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3RLF
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Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to MgAMPPNP
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, MAGNESIUM ION, Maltose transport system permease protein malF, ...
著者Oldham, M.L, Chen, J.
登録日2011-04-19
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Snapshots of the maltose transporter during ATP hydrolysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
6SLM
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BU of 6slm by Molmil
Crystal structure of full-length HPV31 E6 oncoprotein in complex with LXXLL peptide of ubiquitin ligase E6AP
分子名称: GLYCEROL, Maltose/maltodextrin-binding periplasmic protein,Protein E6,Ubiquitin-protein ligase E3A, ZINC ION, ...
著者Conrady, M, Gogl, G, Cousido-Siah, A, Mitschler, A, Trave, G, Simon, C.
登録日2019-08-20
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex Formation.
J.Virol., 95, 2020
4IKM
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X-ray structure of CARD8 CARD domain
分子名称: 1,2-ETHANEDIOL, IODIDE ION, Maltose-binding periplasmic protein, ...
著者Jin, T, Huang, M, Smith, P, Jiang, J, Xiao, T.
登録日2012-12-26
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4606 Å)
主引用文献The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces.
Acta Crystallogr.,Sect.F, 69, 2013
6SQC
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BU of 6sqc by Molmil
Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR containing alpha-methylated Leu1055 and Leu1076
分子名称: 1,2-ETHANEDIOL, Maltose/maltodextrin-binding periplasmic protein,CREB-binding protein, Nuclear receptor coactivator 3, ...
著者Bauer, V, Schmidtgall, B, Gogl, G, Dolenc, j, Osz, J, Kostmann, C, Mitschler, A, Cousido-Siah, A, Rochel, N, Trave, G, Kieffer, B, Torbeev, V.
登録日2019-09-03
公開日2020-09-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Conformational editing of intrinsically disordered protein by alpha-methylation.
Chem Sci, 12, 2020
8JBH
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BU of 8jbh by Molmil
Substance P bound to active human neurokinin 3 receptor in complex with Gq
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein Gq subunit alpha (G324), ...
著者Sun, W.J, Yang, F, Zhang, H.H, Yuan, Q.N, Yin, W.C, Shi, P, Eric, X, Tian, C.L.
登録日2023-05-08
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists.
Cell Discov, 9, 2023
8JBG
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Neurokinin B bound to active human neurokinin 3 receptor in complex with Gq
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein Gq (G324), ...
著者Sun, W.J, Yang, F, Zhang, H.H, Yuan, Q.N, Yin, W.C, Shi, P, Eric, X, Tian, C.L.
登録日2023-05-08
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists.
Cell Discov, 9, 2023
3FIW
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BU of 3fiw by Molmil
Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor
分子名称: DI(HYDROXYETHYL)ETHER, Putative tetR-family transcriptional regulator
著者Singer, A.U, Xu, X, Chang, C, Gu, J, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-12-12
公開日2009-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor
To be Published
6SZH
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BU of 6szh by Molmil
Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GW197
分子名称: 3,5-dimethyl-1~{H}-pyrrole-2-carbonitrile, CALCIUM ION, Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)
著者Thorpe, J.H.
登録日2019-10-02
公開日2020-01-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cocktailed fragment screening by X-ray crystallography of the antibacterial target undecaprenyl pyrophosphate synthase from Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 76, 2020
8AG0
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BU of 8ag0 by Molmil
Crystal structure of mutant PRELID3a-TRIAP1 complex - R53E
分子名称: Maltose/maltodextrin-binding periplasmic protein,TP53-regulated inhibitor of apoptosis 1, PRELI domain containing protein 3A, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Milara, X, Perez-Dorado, J.I, Matthews, S.J.
登録日2022-07-18
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An intermolecular hydrogen bonded network in the PRELID-TRIAP protein family plays a role in lipid sensing.
Biochim Biophys Acta Proteins Proteom, 1871, 2022
8JI0
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BU of 8ji0 by Molmil
Cryo-EM structure of the TcsH-CROP in complex with TMPRSS2
分子名称: Maltose/maltodextrin-binding periplasmic protein,Hemorrhagic toxin, Transmembrane protease serine 2
著者Zhou, R, Tao, L, Zhan, X.
登録日2023-05-25
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin.
Nat Commun, 15, 2024
8AX5
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BU of 8ax5 by Molmil
Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029881
分子名称: (1~{R},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3,5,7(30),20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ...
著者Southall, S.M, Watson, S.P.
登録日2022-08-30
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode.
Acs Med.Chem.Lett., 13, 2022
8AX6
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BU of 8ax6 by Molmil
Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029882
分子名称: (1~{S},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3(30),4,6,20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ...
著者Southall, S.M, Watson, S.P.
登録日2022-08-30
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode.
Acs Med.Chem.Lett., 13, 2022
8AX7
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BU of 8ax7 by Molmil
Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0031448
分子名称: (1~{S},10~{R},20~{E})-10-[(1,7-dimethylindazol-5-yl)methyl]-12-methyl-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3(30),4,6,20,22,24,28-heptaene-8,11,27-trione, ACETATE ION, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, ...
著者Southall, S.M, Watson, S.P.
登録日2022-08-30
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode.
Acs Med.Chem.Lett., 13, 2022
8IZJ
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BU of 8izj by Molmil
Crystal structure of Escherichia coli Adenine Phosphoribosyltransferase (APRT) in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, CHLORIDE ION, ...
著者Yadav, P, Kushwaha, G.S, Bhavesh, N.S.
登録日2023-04-07
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of Escherichia coli Adenine Phosphoribosyltransferase (APRT) in complex with AMP
To Be Published
5JQE
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BU of 5jqe by Molmil
Crystal structure of caspase8 tDED
分子名称: Sugar ABC transporter substrate-binding protein,Caspase-8 chimera
著者Fu, T, Li, Y, Lu, A, Wu, H.
登録日2016-05-04
公開日2016-10-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.157 Å)
主引用文献Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
3FJU
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BU of 3fju by Molmil
Ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase A1
分子名称: ACETATE ION, CACODYLATE ION, Carboxypeptidase A inhibitor, ...
著者Sanglas, L, Aviles, F.X, Huber, R, Gomis-Ruth, F.X, Arolas, J.L.
登録日2008-12-15
公開日2008-12-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite
Proc.Natl.Acad.Sci.USA, 106, 2009
2VRW
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BU of 2vrw by Molmil
Critical structural role for the PH and C1 domains of the Vav1 exchange factor
分子名称: PROTO-ONCOGENE VAV, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, ZINC ION
著者Rapley, J, Tybulewicz, V, Rittinger, K.
登録日2008-04-16
公開日2008-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor.
Embo Rep., 9, 2008
8JAZ
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BU of 8jaz by Molmil
Structure of the alginate epimerase/lyase complexed with di-mannuronic acid
分子名称: CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, mannuronan 5-epimerase
著者Fujiwara, T.
登録日2023-05-07
公開日2024-05-08
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum.
Febs Lett., 598, 2024
8JA6
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Structure of the alginate epimerase/lyase complexed with tri-mannuronic acid
分子名称: ACETATE ION, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, ...
著者Fujiwara, T.
登録日2023-05-05
公開日2024-05-08
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum.
Febs Lett., 598, 2024
8JA4
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BU of 8ja4 by Molmil
Structure of the alginate epimerase/lyase
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ...
著者Fujiwara, T.
登録日2023-05-05
公開日2024-05-08
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum.
Febs Lett., 598, 2024
4IRL
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BU of 4irl by Molmil
X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Jin, T, Huang, M, Smith, P, Xiao, T.
登録日2013-01-15
公開日2013-08-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein.
Acta Crystallogr.,Sect.F, 69, 2013
3SEV
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BU of 3sev by Molmil
Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization
分子名称: CHLORIDE ION, Maltose-binding periplasmic protein, ZINC ION, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
5JON
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BU of 5jon by Molmil
Crystal structure of the unliganded form of HCN2 CNBD
分子名称: Maltose-binding periplasmic protein,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, NITRATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Klenchin, V.A, Chanda, B.
登録日2016-05-02
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.042 Å)
主引用文献Structure and dynamics underlying elementary ligand binding events in human pacemaking channels.
Elife, 5, 2016
4IL0
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BU of 4il0 by Molmil
Crystal structure of GlucDRP from E. coli K-12 MG1655 (EFI target EFI-506058)
分子名称: CITRIC ACID, GLYCEROL, Glucarate dehydratase-related protein
著者Lukk, T, Ghasempur, S, Imker, H.J, Gerlt, J.A, Nair, S.K, Enzyme Function Initiative (EFI)
登録日2012-12-28
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Glucarate dehydratase and its related protein from Escherichia coli form a heterotetrameric complex.
to be published
5JST
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BU of 5jst by Molmil
MBP fused MDV1 coiled coil
分子名称: ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein,Mitochondrial division protein 1, ...
著者Kim, B.-W, Song, H.K.
登録日2016-05-09
公開日2017-03-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献ACCORD: an assessment tool to determine the orientation of homodimeric coiled-coils.
Sci Rep, 7, 2017

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