6SQC

Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR containing alpha-methylated Leu1055 and Leu1076

Summary for 6SQC

Entry DOI	10.2210/pdb6sqc/pdb
Related PRD ID	PRD_900001
Descriptor	Maltose/maltodextrin-binding periplasmic protein,CREB-binding protein, Nuclear receptor coactivator 3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywords	complex, unnatural amino acid, protein binding
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	2
Total formula weight	51957.33
Authors	Bauer, V.,Schmidtgall, B.,Gogl, G.,Dolenc, j.,Osz, J.,Kostmann, C.,Mitschler, A.,Cousido-Siah, A.,Rochel, N.,Trave, G.,Kieffer, B.,Torbeev, V. (deposition date: 2019-09-03, release date: 2020-09-30, Last modification date: 2024-01-31)
Primary citation	Bauer, V.,Schmidtgall, B.,Gogl, G.,Dolenc, J.,Osz, J.,Nomine, Y.,Kostmann, C.,Cousido-Siah, A.,Mitschler, A.,Rochel, N.,Trave, G.,Kieffer, B.,Torbeev, V. Conformational editing of intrinsically disordered protein by alpha-methylation. Chem Sci, 12:1080-1089, 2020 Cited by PubMed: 34163874 DOI: 10.1039/d0sc04482b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.28 Å)

Structure validation