PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4M55	Crystal structure of Human UDP-xylose synthase R236H substitution 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYROPHOSPHATE 2-, SULFATE ION, ... 著者 Walsh Jr, R.M, Polizzi, S.J, Wood, Z.A. 登録日 2013-08-08 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Man o' war mutation in UDP-alpha-D-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation. Biochemistry, 54, 2015
4MD8	Crystal Structure of full-length symmetric CK2 holoenzyme with mutated alpha subunit (F121E) 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Ranchio, A, Battistutta, R. 登録日 2013-08-22 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
4LS5	Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Bacillus subtilis 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, GLYCEROL, POTASSIUM ION 著者 Trajtenberg, F, Larrieux, N, Buschiazzo, A. 登録日 2013-07-22 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
4LSM	Crystal structure of a glycosomal glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi 分子名称: 1,2-ETHANEDIOL, Glyceraldehyde 3-phosphate dehydrogenase, cytosolic, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-07-22 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of a glycosomal glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi TO BE PUBLISHED
4LPB	Crystal structure of a topoisomerase ATPase inhibitor 分子名称: 1-ethyl-3-{5'-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-3,3'-bipyridin-6-yl}urea, Topoisomerase IV subunit B 著者 Boriack-Sjodin, A. 登録日 2013-07-15 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J.Med.Chem., 56, 2013
4LUG	Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana 分子名称: Inorganic pyrophosphatase, SODIUM ION 著者 Grzechowiak, M, Ruszkowski, M, Sikorski, M, Jaskolski, M. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystal structure of Inorganic pyrophosphatase PPA1 from Arabidopsis thaliana To be Published
4LQU	1.60A resolution crystal structure of a superfolder green fluorescent protein (W57G) mutant 分子名称: Green fluorescent protein 著者 Lovell, S, Xia, Y, Vo, B, Battaile, K.P, Egan, C, Karanicolas, J. 登録日 2013-07-19 公開日 2013-12-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation. J.Am.Chem.Soc., 135, 2013
4LRG	Structure of BRD4 bromodomain 1 with a dimethyl thiophene isoxazole azepine carboxamide 分子名称: 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-[1,2]oxazolo[5,4-c]thieno[2,3-e]azepin-6-yl]acetamide, Bromodomain-containing protein 4 著者 Ravichandran, S, Jayaram, H, Poy, F, Gehling, V, Hewitt, M, Vaswani, R, Leblanc, Y, Cote, A, Nasveschuk, C, Taylor, A, Harmange, J.-C, Audia, J, Pardo, E, Joshi, S, Sandy, P, Mertz, J, Sims, R, Bergeron, L, Bryant, B, Yellapuntala, S, Nandana, B.S, Birudukota, S, Albrecht, B, Bellon, S. 登録日 2013-07-19 公開日 2013-08-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors. ACS Med Chem Lett, 4, 2013
4LV4	A noncompetitive inhibitor for M. tuberculosis's class IIa fructose 1,6-bisphosphate aldolase 分子名称: 8-hydroxyquinoline-2-carboxylic acid, ACETATE ION, Fructose-bisphosphate aldolase, ... 著者 Capodagli, G.C, Pegan, S.D. 登録日 2013-07-25 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 A Noncompetitive Inhibitor for Mycobacterium tuberculosis's Class IIa Fructose 1,6-Bisphosphate Aldolase. Biochemistry, 53, 2014
4LU4	Crystal Structure of the N-terminal Fic Domain of a Putative Cell Filamentation protein (VirB-translocated Bep effector protein) from Bartonella quintana 分子名称: BROMIDE ION, CHLORIDE ION, IODIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-07-24 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
4LYF	Crystal Structure of small molecule vinylsulfonamide 8 covalently bound to K-Ras G12C 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, N-{1-[N-(4,5-dichloro-2-hydroxyphenyl)glycyl]piperidin-4-yl}ethanesulfonamide 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-07-31 公開日 2013-11-27 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.568 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
4LYW	Crystal Structure of BRD4(1) bound to inhibitor XD14 分子名称: 4-acetyl-N-[5-(diethylsulfamoyl)-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide, Bromodomain-containing protein 4 著者 Wohlwend, D, Gerhardt, S, Einsle, O. 登録日 2013-07-31 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52, 2013
4LZZ	Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transcriptional regulator (NtrC family), ... 著者 Sysoeva, T.A, Chowdhury, S, Guo, L, Nixon, B.T. 登録日 2013-08-01 公開日 2013-12-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Nucleotide-induced asymmetry within ATPase activator ring drives sigma 54-RNAP interaction and ATP hydrolysis. Genes Dev., 27, 2013
4M2Q	Crystal structure of non-myristoylated recoverin with Cysteine-39 oxidized to sulfenic acid 分子名称: CALCIUM ION, Recoverin 著者 Prem Kumar, R, Chakrabarti, K, Kern, D, Oprian, D.D. 登録日 2013-08-05 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca2+ to Recoverin. J.Biol.Chem., 288, 2013
4LM5	Crystal structure of Pim1 in complex with 2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol (resulting from displacement of SKF86002) 分子名称: 2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol, GLYCEROL, Serine/threonine-protein kinase pim-1 著者 Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. 登録日 2013-07-10 公開日 2014-02-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002. Acta Crystallogr.,Sect.D, 70, 2014
4L8G	Crystal Structure of K-Ras G12C, GDP-bound 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-06-17 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.521 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
4L8Q	Crystal structure of Canavalia grandiflora seed lectin complexed with X-Man. 分子名称: 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CADMIUM ION, CALCIUM ION, ... 著者 Barroso-Neto, I.L, Rocha, B.A.M, Simoes, R.C, Bezerra, M.J.B, Pereira-Junior, F.N, Osterne, V.J.S, Nascimento, K.S, Nagano, C.S, Delatorre, P, Sampaio, A.H, Cavada, B.S. 登録日 2013-06-17 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Vasorelaxant activity of Canavalia grandiflora seed lectin: A structural analysis. Arch.Biochem.Biophys., 543, 2014
4L9O	Crystal Structure of the Sec13-Sec16 blade-inserted complex from Pichia pastoris 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 McMahon, C, Jeffrey, P.D, Hughson, F.M. 登録日 2013-06-18 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Sec16 influences transitional ER sites by regulating rather than organizing COPII. Mol Biol Cell, 24, 2013
4LC2	Crystal structure of the bromodomain of human BRPF1B 分子名称: 1,2-ETHANEDIOL, NITRATE ION, Peregrin 著者 Tallant, C, Nunez-Alonso, G, Savitsky, P, Picaud, S, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2013-06-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the bromodomain of human BRPF1B TO BE PUBLISHED
4LE2	Crystal structure of the unphosphorylated receiver domain of DesR in the active state 分子名称: PHOSPHATE ION, POTASSIUM ION, Transcriptional regulatory protein DesR 著者 Trajtenberg, F, Larrieux, N, Buschiazzo, A. 登録日 2013-06-25 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio, 5, 2014
4KZT	Structure mmNAGS bound with L-arginine 分子名称: ARGININE, DI(HYDROXYETHYL)ETHER, N-acetylglutamate kinase / N-acetylglutamate synthase 著者 Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M, Shi, D. 登録日 2013-05-30 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of N-acetyl-L-glutamate synthase/kinase from Maricaulis maris with the allosteric inhibitor L-arginine bound. Biochem.Biophys.Res.Commun., 437, 2013
4L1B	Crystal Structure of p110alpha complexed with niSH2 of p85alpha 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, SULFATE ION 著者 Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. 登録日 2013-06-03 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.586 Å) 主引用文献 Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
4L9W	Crystal Structure of H-Ras G12C, GMPPNP-bound 分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-06-18 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
4LBW	Identifying ligand binding hot spots in proteins using brominated fragments 分子名称: AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ... 著者 Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P. 登録日 2013-06-21 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.741 Å) 主引用文献 Identifying ligand-binding hot spots in proteins using brominated fragments. Acta Crystallogr.,Sect.F, 69, 2013
4LGO	Crystal Structure of N-terminal domain 1 of VompD from Bartonella quintana 分子名称: 1,2-ETHANEDIOL, VompD 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-06-28 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of N-terminal domain 1 of VompD from Bartonella quintana To be Published

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