4LV4
A noncompetitive inhibitor for M. tuberculosis's class IIa fructose 1,6-bisphosphate aldolase
Summary for 4LV4
| Entry DOI | 10.2210/pdb4lv4/pdb |
| Related | 3EKL 3EKZ 3ELF 4A21 4A22 4DEF 4DEL |
| Descriptor | Fructose-bisphosphate aldolase, ZINC ION, 8-hydroxyquinoline-2-carboxylic acid, ... (6 entities in total) |
| Functional Keywords | class ii fructose-1, 6-bisphosphate aldolase, zinc enzyme, mycobacterium tuberculosis, dihydroxyacetone, glyceraldehyde-3-phosphate, aldol condensation, glycolysis, lyase, metal-binding, 8-hydroxyquinoline-2-carboxylic acid, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 37952.46 |
| Authors | Capodagli, G.C.,Pegan, S.D. (deposition date: 2013-07-25, release date: 2014-01-08, Last modification date: 2023-09-20) |
| Primary citation | Capodagli, G.C.,Sedhom, W.G.,Jackson, M.,Ahrendt, K.A.,Pegan, S.D. A Noncompetitive Inhibitor for Mycobacterium tuberculosis's Class IIa Fructose 1,6-Bisphosphate Aldolase. Biochemistry, 53:202-213, 2014 Cited by PubMed: 24325645DOI: 10.1021/bi401022b PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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