4LV4
A noncompetitive inhibitor for M. tuberculosis's class IIa fructose 1,6-bisphosphate aldolase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fructose-bisphosphate aldolase | polymer | 349 | 37276.1 | 1 | UniProt (P67475) Pfam (PF01116) UniProt (by SIFTS) (P9WQA3) | Mycobacterium tuberculosis | FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | 8-hydroxyquinoline-2-carboxylic acid | non-polymer | 189.2 | 1 | Chemie (8HC) | |||
| 4 | E, F (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | G (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 6 | H (A) | water | water | 18.0 | 357 | Chemie (HOH) |
Sequence modifications
A: 1 - 344 (UniProt: P67475)
| PDB | External Database | Details |
|---|---|---|
| His 345 | - | expression tag |
| His 346 | - | expression tag |
| His 347 | - | expression tag |
| His 348 | - | expression tag |
| His 349 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37276.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 676.4 | |
| All* | Total formula weight | 37952.5 |
