6E63
| Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody TB31F | 分子名称: | GLYCEROL, Pf48/45, TB31F Fab heavy chain, ... | 著者 | Kundu, P, Semesi, A, Julien, J.P. | 登録日 | 2018-07-23 | 公開日 | 2018-11-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nat Commun, 9, 2018
|
|
6W2B
| Anomalous bromine signal reveals the position of Br-paroxetine complexed with the serotonin transporter at the central site | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 heavy chain antibody fragment, 8B6 light chain antibody fragment, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-03-05 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (4.7 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
|
|
3NCJ
| |
1F58
| IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323 | 分子名称: | Envelope glycoprotein gp120, PROTEIN (IGG1 ANTIBODY 58.2 (HEAVY CHAIN)), PROTEIN (IGG1 ANTIBODY 58.2 (LIGHT CHAIN)) | 著者 | Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A. | 登録日 | 1998-10-21 | 公開日 | 1999-02-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Structure Fold.Des., 7, 1999
|
|
7NEG
| Crystal structure of the N501Y mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-269 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody COVOX-269 Fab heavy chain, Antibody COVOX-269 Fab light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-02-04 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera. Cell, 184, 2021
|
|
7R74
| |
4KHX
| |
2JSF
| |
7SD2
| |
6NB4
| MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
|
|
6NB7
| SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
|
|
6NB6
| SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
|
|
2Y5T
| Crystal structure of the pathogenic autoantibody CIIC1 in complex with the triple-helical C1 peptide | 分子名称: | C1, CHLORIDE ION, CIIC1 FAB FRAGMENT HEAVY CHAIN, ... | 著者 | Dobritzsch, D, Lindh, I, Schneider, N, Uysal, H, Nandakumar, K.S, Burkhardt, H, Schneider, G, Holmdahl, R. | 登録日 | 2011-01-17 | 公開日 | 2011-12-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of an Arthritogenic Anticollagen Immune Complex. Arthritis Rheum., 63, 2011
|
|
3IVK
| Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment | 分子名称: | CADMIUM ION, CHLORIDE ION, Fab heavy chain, ... | 著者 | Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A. | 登録日 | 2009-09-01 | 公開日 | 2010-03-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science, 326, 2009
|
|
8ASY
| SARS-CoV-2 Omicron BA.2.75 RBD in complex with ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Zhou, D, Huo, J, Ren, J, Stuart, D.I. | 登録日 | 2022-08-22 | 公開日 | 2023-01-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75. Cell Rep, 42, 2022
|
|
6Z2L
| |
8BW0
| Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 5, ... | 著者 | Kumar, A, Bertrand, T, Rapisarda, C, Rak, A. | 登録日 | 2022-12-06 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structural insights into epitope-paratope interactions of monoclonal antibody targeting CEACAM5-expressing tumors Res Sq, 2023
|
|
7A3S
| Crystal structure of dengue 3 virus envelope glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SULFATE ION | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Navarro-Sanchez, E, Rey, F.A. | 登録日 | 2020-08-18 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. Cell, 184, 2021
|
|
5YFI
| Crystal structure of the anti-human prostaglandin E receptor EP4 antibody Fab fragment | 分子名称: | Heavy chain of Fab fragment, Light chain of Fab fragment, ZINC ION | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | 登録日 | 2017-09-21 | 公開日 | 2018-12-05 | 最終更新日 | 2019-03-06 | 実験手法 | X-RAY DIFFRACTION (1.848 Å) | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface. Nat. Chem. Biol., 15, 2019
|
|
8Q7S
| Crystal structure of the SARS-CoV-2 RBD (Wuhan) with neutralizing VHHs Ma6F06 and Re21H01 | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ... | 著者 | Guttler, T, Aksu, M, Gorlich, D. | 登録日 | 2023-08-16 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters. Antiviral Res., 221, 2023
|
|
6JMQ
| LAT1-CD98hc complex bound to MEM-108 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | 著者 | Lee, Y, Nishizawa, T, Kusakizako, T, Oda, K, Ishitani, R, Nakane, T, Nureki, O. | 登録日 | 2019-03-13 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nat.Struct.Mol.Biol., 26, 2019
|
|
6JMR
| CD98hc extracellular domain bound to HBJ127 Fab and MEM-108 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | 著者 | Lee, Y, Nishizawa, T, Kusakizako, T, Oda, K, Ishitani, R, Yokoyama, T, Nakane, T, Shirouzu, M, Nureki, O. | 登録日 | 2019-03-13 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nat.Struct.Mol.Biol., 26, 2019
|
|
5J13
| |
6VOS
| Crystal structure of macaque anti-HIV-1 antibody RM20J | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ... | 著者 | Yuan, M, Wilson, I.A. | 登録日 | 2020-01-31 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathog., 16, 2020
|
|
6VSR
| |