2Y5T
Crystal structure of the pathogenic autoantibody CIIC1 in complex with the triple-helical C1 peptide
Summary for 2Y5T
Entry DOI | 10.2210/pdb2y5t/pdb |
Descriptor | CIIC1 FAB FRAGMENT HEAVY CHAIN, CIIC1 FAB FRAGMENT LIGHT CHAIN, C1, ... (7 entities in total) |
Functional Keywords | immune system, antibody, rheumatoid arthritis, arthritogenic |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Total number of polymer chains | 5 |
Total formula weight | 58871.68 |
Authors | Dobritzsch, D.,Lindh, I.,Schneider, N.,Uysal, H.,Nandakumar, K.S.,Burkhardt, H.,Schneider, G.,Holmdahl, R. (deposition date: 2011-01-17, release date: 2011-12-14, Last modification date: 2023-12-20) |
Primary citation | Dobritzsch, D.,Lindh, I.,Uysal, H.,Nandakumar, K.S.,Burkhardt, H.,Schneider, G.,Holmdahl, R. Crystal Structure of an Arthritogenic Anticollagen Immune Complex. Arthritis Rheum., 63:3740-, 2011 Cited by PubMed: 22127694DOI: 10.1002/ART.30611 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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