5YFI

Crystal structure of the anti-human prostaglandin E receptor EP4 antibody Fab fragment

Summary for 5YFI

Entry DOI	10.2210/pdb5yfi/pdb
Descriptor	Light chain of Fab fragment, Heavy chain of Fab fragment, ZINC ION, ... (4 entities in total)
Functional Keywords	antibody, immune system
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	54581.40
Authors	Toyoda, Y.,Morimoto, K.,Suno, R.,Horita, S.,Iwata, S.,Kobayashi, T. (deposition date: 2017-09-21, release date: 2018-12-05, Last modification date: 2019-03-06)
Primary citation	Toyoda, Y.,Morimoto, K.,Suno, R.,Horita, S.,Yamashita, K.,Hirata, K.,Sekiguchi, Y.,Yasuda, S.,Shiroishi, M.,Shimizu, T.,Urushibata, Y.,Kajiwara, Y.,Inazumi, T.,Hotta, Y.,Asada, H.,Nakane, T.,Shiimura, Y.,Nakagita, T.,Tsuge, K.,Yoshida, S.,Kuribara, T.,Hosoya, T.,Sugimoto, Y.,Nomura, N.,Sato, M.,Hirokawa, T.,Kinoshita, M.,Murata, T.,Takayama, K.,Yamamoto, M.,Narumiya, S.,Iwata, S.,Kobayashi, T. Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface. Nat. Chem. Biol., 15:18-26, 2019 Cited by PubMed: 30510193 DOI: 10.1038/s41589-018-0131-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.848 Å)

Structure validation