8BW0
Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab
Summary for 8BW0
| Entry DOI | 10.2210/pdb8bw0/pdb |
| EMDB information | 16279 |
| Descriptor | Tusamitamab Fab heavy Chain, Tusamitamab Light Chain, Carcinoembryonic antigen-related cell adhesion molecule 5, ... (6 entities in total) |
| Functional Keywords | ceacam5, tusamitamab, cancer, cell adhesion, cryo-em, small molecular weight, fab, a3-b3, human membrane protein |
| Biological source | Mus sp. More |
| Total number of polymer chains | 3 |
| Total formula weight | 71783.15 |
| Authors | Kumar, A.,Bertrand, T.,Rapisarda, C.,Rak, A. (deposition date: 2022-12-06, release date: 2024-01-24) |
| Primary citation | Rak, A.,Kumar, A.,Duffi, F.,Gagnaire, M.,Rapisarda, C.,Bertrand, T. Structural insights into epitope-paratope interactions of monoclonal antibody targeting CEACAM5-expressing tumors Res Sq, 2023 Cited by DOI: 10.21203/rs.3.rs-3235785/v1PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.11 Å) |
Structure validation
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