8BW0
Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | Tusamitamab Fab heavy Chain | polymer | 234 | 24833.7 | 1 | Mus sp. | ||
2 | L | Tusamitamab Light Chain | polymer | 214 | 23497.1 | 1 | Mus sp. | ||
3 | C | Carcinoembryonic antigen-related cell adhesion molecule 5 | polymer | 193 | 20883.0 | 1 | UniProt (P06731) Pfam (PF13927) In PDB | Homo sapiens (human) | Carcinoembryonic antigen,CEA,Meconium antigen 100 |
4 | A, D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
5 | B | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G82348BZ) | |||
6 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
C: 499 - 685 (UniProt: P06731)
PDB | External Database | Details |
---|---|---|
His 686 | - | expression tag |
His 687 | - | expression tag |
His 688 | - | expression tag |
His 689 | - | expression tag |
His 690 | - | expression tag |
His 691 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 69213.8 | |
Branched | Number of molecules | 3 |
Total formula weight | 1905.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 663.6 | |
All* | Total formula weight | 71783.2 |