2QKC
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![BU of 2qkc by Molmil](/molmil-images/mine/2qkc) | Structural and Kinetic Study of the Differences between Human and E.coli Manganese Superoxide Dismutases | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn] | 著者 | Zheng, J, Domsic, J.F, Cabelli, D, McKenna, R, Silverman, D.N. | 登録日 | 2007-07-10 | 公開日 | 2008-07-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and kinetic study of differences between human and Escherichia coli manganese superoxide dismutases. Biochemistry, 46, 2007
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2QLB
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![BU of 2qlb by Molmil](/molmil-images/mine/2qlb) | Crystal Structure of caspase-7 with inhibitor AC-ESMD-CHO | 分子名称: | CITRIC ACID, Caspase-7, Inhibitor AC-ESMD-CHO, ... | 著者 | Agniswamy, J, Fang, B, Weber, I. | 登録日 | 2007-07-12 | 公開日 | 2007-08-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
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2QQS
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2R0M
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![BU of 2r0m by Molmil](/molmil-images/mine/2r0m) | The effect of a Glu370Asp Mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate | 分子名称: | 4-nitrobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase | 著者 | Rao, K.S, Fu, Z, Albro, M, Narayanan, B, Baddam, S, Lee, H.J, Kim, J.J, Frerman, F.E. | 登録日 | 2007-08-20 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate. Biochemistry, 46, 2007
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2QTD
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2R3M
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![BU of 2r3m by Molmil](/molmil-images/mine/2r3m) | Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor | 分子名称: | Cell division protein kinase 2, N-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine | 著者 | Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. | 登録日 | 2007-08-29 | 公開日 | 2008-01-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
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2R3F
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![BU of 2r3f by Molmil](/molmil-images/mine/2r3f) | Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor | 分子名称: | 5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 | 著者 | Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. | 登録日 | 2007-08-29 | 公開日 | 2008-01-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
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2R3Q
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![BU of 2r3q by Molmil](/molmil-images/mine/2r3q) | Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor | 分子名称: | 3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide, Cell division protein kinase 2 | 著者 | Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. | 登録日 | 2007-08-29 | 公開日 | 2008-01-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
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2R0U
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![BU of 2r0u by Molmil](/molmil-images/mine/2r0u) | Crystal Structure of Chek1 in Complex with Inhibitor 54 | 分子名称: | 6-(3-aminopropyl)-4-(3-hydroxyphenyl)-9-(1H-pyrazol-4-yl)benzo[h]isoquinolin-1(2H)-one, Serine/threonine-protein kinase Chk1 | 著者 | Yan, Y, Ikuta, M. | 登録日 | 2007-08-21 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase. Bioorg.Med.Chem.Lett., 17, 2007
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2R6W
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![BU of 2r6w by Molmil](/molmil-images/mine/2r6w) | Estrogen receptor alpha ligand-binding domain complexed to a SERM | 分子名称: | Estrogen receptor, [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl]{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl}methanone | 著者 | Wang, Y. | 登録日 | 2007-09-06 | 公開日 | 2008-04-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2R92
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![BU of 2r92 by Molmil](/molmil-images/mine/2r92) | Elongation complex of RNA polymerase II with artificial RdRP scaffold | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Lehmann, E, Brueckner, F, Cramer, P. | 登録日 | 2007-09-12 | 公開日 | 2007-11-27 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
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2RFD
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![BU of 2rfd by Molmil](/molmil-images/mine/2rfd) | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | 分子名称: | ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor, SULFATE ION | 著者 | Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. | 登録日 | 2007-09-28 | 公開日 | 2007-12-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature, 450, 2007
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2RCW
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![BU of 2rcw by Molmil](/molmil-images/mine/2rcw) | PARP complexed with A620223 | 分子名称: | Poly [ADP-ribose] polymerase 1, trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium | 著者 | Park, C.H. | 登録日 | 2007-09-20 | 公開日 | 2008-09-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | PARP complexed with A620223 To be Published
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2REI
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![BU of 2rei by Molmil](/molmil-images/mine/2rei) | Kinase domain of human ephrin type-A receptor 7 (Epha7) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ephrin type-A receptor 7 | 著者 | Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-09-26 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Kinase Domain of Human Ephrin Type-A Receptor 7 (Epha7). To be Published
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2RFI
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![BU of 2rfi by Molmil](/molmil-images/mine/2rfi) | Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide | 分子名称: | Histone H3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... | 著者 | Min, J, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2007-09-30 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Structural biology of human H3K9 methyltransferases Plos One, 5, 2010
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2RGZ
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![BU of 2rgz by Molmil](/molmil-images/mine/2rgz) | Ensemble refinement of the protein crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme | 分子名称: | Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Bianchetti, C.M, Bingman, C.A, Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2007-10-05 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2. J.Biol.Chem., 282, 2007
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2RBL
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2RD7
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![BU of 2rd7 by Molmil](/molmil-images/mine/2rd7) | Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins | 分子名称: | CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain | 著者 | Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M. | 登録日 | 2007-09-21 | 公開日 | 2008-05-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement. J. Biol. Chem., 286, 2011
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2RF9
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![BU of 2rf9 by Molmil](/molmil-images/mine/2rf9) | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | 分子名称: | ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor | 著者 | Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. | 登録日 | 2007-09-28 | 公開日 | 2007-12-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature, 450, 2007
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1SGR
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1THP
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![BU of 1thp by Molmil](/molmil-images/mine/1thp) | STRUCTURE OF HUMAN ALPHA-THROMBIN Y225P MUTANT BOUND TO D-PHE-PRO-ARG-CHLOROMETHYLKETONE | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, PROTEIN (THROMBIN HEAVY CHAIN), PROTEIN (THROMBIN LIGHT CHAIN) | 著者 | Caccia, S, Futterer, K, Di Cera, E, Waksman, G. | 登録日 | 1999-01-26 | 公開日 | 1999-03-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Unexpected crucial role of residue 225 in serine proteases. Proc.Natl.Acad.Sci.USA, 96, 1999
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1FYB
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![BU of 1fyb by Molmil](/molmil-images/mine/1fyb) | SOLUTION STRUCTURE OF C1-T1, A TWO-DOMAIN PROTEINASE INHIBITOR DERIVED FROM THE CIRCULAR PRECURSOR PROTEIN NA-PROPI FROM NICOTIANA ALATA | 分子名称: | PROTEINASE INHIBITOR | 著者 | Craik, D.J, Schirra, H.J, Scanlon, M.J, Anderson, M.A. | 登録日 | 2000-09-28 | 公開日 | 2001-02-21 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata. J.Mol.Biol., 306, 2001
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1SGP
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1SGN
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![BU of 1sgn by Molmil](/molmil-images/mine/1sgn) | ASN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | 分子名称: | Ovomucoid, PHOSPHATE ION, Streptogrisin B | 著者 | Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. | 登録日 | 1999-03-25 | 公開日 | 2003-08-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with
Streptomyces griseus Protease B at Various pHs To be Published
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1SGY
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![BU of 1sgy by Molmil](/molmil-images/mine/1sgy) | TYR 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | 分子名称: | Ovomucoid, PHOSPHATE ION, Streptogrisin B | 著者 | Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. | 登録日 | 1999-03-25 | 公開日 | 2003-08-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's To be Published
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