8T1H
 
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8EJ4
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5OTE
 | | MRCK beta in complex with BDP-00008900 | | 分子名称: | 1,2-ETHANEDIOL, 2-[4-[(6~{S})-1,8-diazaspiro[5.5]undecan-8-yl]-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]-1,3-thiazole, CHLORIDE ION, ... | | 著者 | Schuettelkopf, A.W. | | 登録日 | 2017-08-21 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.
Cancer Res., 78, 2018
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9B4R
 | | Crystal structure of MRAS bound to GMPPNP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras, ... | | 著者 | Czyzyk, D.J, Simanshu, D.K. | | 登録日 | 2024-03-21 | | 公開日 | 2025-01-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into isoform-specific RAS-PI3K alpha interactions and the role of RAS in PI3K alpha activation.
Nat Commun, 16, 2025
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9FIY
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9C1A
 | | Crystal structure of GDP-bound human M-RAS protein in crystal form I | | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Bester, S.M, Abrahamsen, R, Samora, L.R, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-05-28 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Crystal structure of the GDP-bound human M-RAS protein in two crystal forms.
Acta Crystallogr.,Sect.F, 80, 2024
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9C1B
 | | Crystal structure of GDP-bound human M-RAS protein in crystal form II | | 分子名称: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Bester, S.M, Abrahamsen, R, Samora, L.R, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-05-28 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal structure of the GDP-bound human M-RAS protein in two crystal forms.
Acta Crystallogr.,Sect.F, 80, 2024
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9FIX
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9IKQ
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5OOL
 | | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | | 登録日 | 2017-08-08 | | 公開日 | 2017-09-13 | | 最終更新日 | 2025-04-09 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
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4L4T
 | | Structure of human MAIT TCR in complex with human MR1-6-FP | | 分子名称: | 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ... | | 著者 | Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J. | | 登録日 | 2013-06-09 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013
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5OOM
 | | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | | 登録日 | 2017-08-08 | | 公開日 | 2017-09-13 | | 最終更新日 | 2025-04-09 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
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9B0S
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5OTF
 | | MRCK beta in complex with BDP-00009066 | | 分子名称: | (6~{S})-8-(3-pyrimidin-4-yl-1~{H}-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Schuettelkopf, A.W. | | 登録日 | 2017-08-21 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.
Cancer Res., 78, 2018
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4JJH
 | | Crystal structure of the D1 domain from human Nectin-4 extracellular fragment [PSI-NYSGRC-005624] | | 分子名称: | 1,2-ETHANEDIOL, Poliovirus receptor-related protein 4 | | 著者 | Kumar, P.R, Bonanno, J, Ahmed, M, Banu, R, Bhosle, R, Calarese, D, Celikigil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S, Glenn, A.S, Hillerich, B, Khafizov, K, Love, J, Patel, H, Seidel, R, Stead, M, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | | 登録日 | 2013-03-07 | | 公開日 | 2013-03-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of the D1 domain of human Nectin-4 extracellular fragment [NYSGRC-005624]
to be published
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9FQR
 | | 96-nm repeat of axonemal doublet microtubules from bovine sperm | | 分子名称: | A-kinase anchoring protein 14, ATP6V1F neighbor, Actin, ... | | 著者 | Leung, M.R, Sun, C, Zeng, J, Anderson, J.R, Niu, Q, Huang, W, Noteborn, W.E.M, Brown, A, Zeev-Ben-Mordehai, T, Zhang, R. | | 登録日 | 2024-06-21 | | 公開日 | 2025-03-26 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Structural diversity of axonemes across mammalian motile cilia.
Nature, 637, 2025
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5NI7
 | | Ligand complex of RORg LBD | | 分子名称: | DIMETHYL SULFOXIDE, Nuclear receptor ROR-gamma, SODIUM ION, ... | | 著者 | Xue, Y, Aagaard, A, Narjes, F. | | 登録日 | 2017-03-23 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design.
J. Med. Chem., 61, 2018
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8Y6P
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5MS5
 | | Low-salt structure of RavZ LIR2-fused human LC3B | | 分子名称: | GLYCEROL, RavZ,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | | 著者 | Pantoom, S, Vetter, I.R, Wu, Y.W. | | 登録日 | 2016-12-31 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
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9B0Q
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9FIW
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5MS6
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8UA4
 | | Structure of eastern equine encephalitis virus VLP in complex with VLDLR LA1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ... | | 著者 | Abraham, J, Yang, P, Li, W, Fan, X, Pan, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-08-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural basis for VLDLR recognition by eastern equine encephalitis virus.
Nat Commun, 15, 2024
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8UA9
 | | Structure of eastern equine encephalitis virus VLP unliganded quasi-threefold spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Envelope glycoprotein E1, ... | | 著者 | Abraham, J, Yang, P, Li, W, Fan, X, Pan, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-08-14 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for VLDLR recognition by eastern equine encephalitis virus.
Nat Commun, 15, 2024
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8Y6Q
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