6MNZ
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![BU of 6mnz by Molmil](/molmil-images/mine/6mnz) | Crystal structure of RibBX, a two domain 3,4-dihydroxy-2-butanone 4-phosphate synthase from A. baumannii. | 分子名称: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, CHLORIDE ION, SULFATE ION | 著者 | Wang, J, Gonzalez-Gutierrez, G, Giedroc, D.P. | 登録日 | 2018-10-03 | 公開日 | 2019-04-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Multi-metal Restriction by Calprotectin Impacts De Novo Flavin Biosynthesis in Acinetobacter baumannii. Cell Chem Biol, 26, 2019
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8WM0
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![BU of 8wm0 by Molmil](/molmil-images/mine/8wm0) | Crystal structure of TNIK-thiopeptide wTP3 complex | 分子名称: | ADENOSINE, THIOPEPTIDE wTP3, TRAF2 and NCK-interacting protein kinase | 著者 | Hamada, K, Kobayashi, S, Vinogradov, A.A, Zhang, Y, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | 登録日 | 2023-10-01 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. J.Am.Chem.Soc., 2024
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8GSA
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5K7H
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![BU of 5k7h by Molmil](/molmil-images/mine/5k7h) | Crystal structure of AibR in complex with the effector molecule isovaleryl coenzyme A | 分子名称: | CHLORIDE ION, Isovaleryl-coenzyme A, NICKEL (II) ION, ... | 著者 | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-05-26 | 公開日 | 2016-12-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res., 45, 2017
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5KEZ
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5JD2
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![BU of 5jd2 by Molmil](/molmil-images/mine/5jd2) | SFX structure of corestreptavidin-selenobiotin complex | 分子名称: | 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-selenopheno[3,4-d]imidazol-4-yl]pentanoic acid, Streptavidin | 著者 | DeMirci, H, Hunter, M.S, Boutet, S. | 登録日 | 2016-04-15 | 公開日 | 2016-11-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Selenium single-wavelength anomalous diffraction de novo phasing using an X-ray-free electron laser. Nat Commun, 7, 2016
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5K7F
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![BU of 5k7f by Molmil](/molmil-images/mine/5k7f) | Crystal structure of apo AibR | 分子名称: | ACETATE ION, Transcriptional regulator, TetR family | 著者 | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-05-26 | 公開日 | 2016-12-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res., 45, 2017
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6DHY
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6DHZ
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6BRR
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3S2S
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3S70
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![BU of 3s70 by Molmil](/molmil-images/mine/3s70) | Crystal structure of active caspase-6 bound with Ac-VEID-CHO solved by As-SAD | 分子名称: | ACETATE ION, CACODYLATE ION, Caspase-6, ... | 著者 | Su, X.-D, Liu, X, Wang, X.-J. | 登録日 | 2011-05-26 | 公開日 | 2012-04-11 | 最終更新日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (1.625 Å) | 主引用文献 | Get phases from arsenic anomalous scattering: de novo SAD phasing of two protein structures crystallized in cacodylate buffer Plos One, 6, 2011
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6W3D
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6W3G
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6W3F
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7BX2
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6PLF
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![BU of 6plf by Molmil](/molmil-images/mine/6plf) | Crystal structure of human PHGDH complexed with Compound 1 | 分子名称: | 1,2-ETHANEDIOL, 4-{(1S)-1-[(5-chloro-6-{[(5S)-2-oxo-1,3-oxazolidin-5-yl]methoxy}-1H-indole-2-carbonyl)amino]-2-hydroxyethyl}benzoic acid, D-3-phosphoglycerate dehydrogenase | 著者 | Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K. | 登録日 | 2019-06-30 | 公開日 | 2019-07-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. Bioorg.Med.Chem.Lett., 29, 2019
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6PLG
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![BU of 6plg by Molmil](/molmil-images/mine/6plg) | Crystal structure of human PHGDH complexed with Compound 15 | 分子名称: | (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid, D-3-phosphoglycerate dehydrogenase, D-MALATE | 著者 | Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K. | 登録日 | 2019-06-30 | 公開日 | 2019-07-24 | 最終更新日 | 2019-09-04 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. Bioorg.Med.Chem.Lett., 29, 2019
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6RA4
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8AP1
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![BU of 8ap1 by Molmil](/molmil-images/mine/8ap1) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with two GTP molecules poised for de novo initiation (IC2) | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | 登録日 | 2022-08-09 | 公開日 | 2023-08-23 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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4ONJ
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4ONQ
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4E8U
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4N3P
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![BU of 4n3p by Molmil](/molmil-images/mine/4n3p) | Crystal Structure of De Novo designed Serine Hydrolase OSH18, Northeast Structural Genomics Consortium (NESG) Target OR396 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Mao, L, Xiao, R, Kogan, S, Maglaqui, M, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-10-07 | 公開日 | 2013-11-13 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Crystal Structure of De Novo designed Serine Hydrolase OSH18, Northeast Structural Genomics Consortium (NESG) Target OR396 To be Published
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2N2T
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![BU of 2n2t by Molmil](/molmil-images/mine/2n2t) | Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303 | 分子名称: | OR303 | 著者 | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Hamilton, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-05-14 | 公開日 | 2015-09-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303 To be Published
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