8AP1

Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with two GTP molecules poised for de novo initiation (IC2)

Summary for 8AP1

Entry DOI	10.2210/pdb8ap1/pdb
Related	6YMV 6YMW 8AP1 8ATT 8ATV 8ATW 8C5S 8C5U 8Q63
EMDB information	15556
Descriptor	Mitochondrial transcription factor 1, DNA-directed RNA polymerase, mitochondrial, Non-template DNA (33-MER), ... (6 entities in total)
Functional Keywords	gene transcription, polymerase, rdrp, mtf1, rpo41, polrmt, mtrnap, dna, transcription initiation, rna polymerase, mitochondria, transcription
Biological source	Saccharomyces cerevisiae S288C More
Total number of polymer chains	4
Total formula weight	205800.71
Authors	Goovaerts, Q.,Shen, J.,Patel, S.S.,Das, K. (deposition date: 2022-08-09, release date: 2023-08-23, Last modification date: 2023-11-01)
Primary citation	Goovaerts, Q.,Shen, J.,De Wijngaert, B.,Basu, U.,Patel, S.S.,Das, K. Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622:872-879, 2023 Cited by PubMed: 37821701 DOI: 10.1038/s41586-023-06643-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.47 Å)

Structure validation