7DXB
| Structure of TRPC3 at 2.7 angstrom in high calcium state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Chen, L, Guo, W. | 登録日 | 2021-01-18 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110, 2022
|
|
7DXC
| Structure of TRPC3 at 3.06 angstrom in low calcium state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, Short transient receptor potential channel 3, ... | 著者 | Chen, L, Guo, W. | 登録日 | 2021-01-18 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110, 2022
|
|
7DXG
| Structure of SAR7334-bound TRPC6 at 2.9 angstrom | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile, CALCIUM ION, ... | 著者 | Chen, L, Guo, W. | 登録日 | 2021-01-18 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110, 2022
|
|
7DXE
| |
7DXF
| |
7WF3
| Composite map of human Kv1.3 channel in apo state with beta subunits | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, ... | 著者 | Tyagi, A, Ahmed, T, Jian, S, Bajaj, S, Ong, S.T, Goay, S.S.M, Zhao, Y, Vorobyov, I, Tian, C, Chandy, K.G, Bhushan, S. | 登録日 | 2021-12-25 | 公開日 | 2022-02-09 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7WF4
| Composite map of human Kv1.3 channel in dalazatide-bound state with beta subunits | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, ... | 著者 | Tyagi, A, Ahmed, T, Jian, S, Bajaj, S, Ong, S.T, Goay, S.S.M, Zhao, Y, Vorobyov, I, Tian, C, Chandy, K.G, Bhushan, S. | 登録日 | 2021-12-25 | 公開日 | 2022-02-09 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7PHI
| Human voltage-gated potassium channel Kv3.1 (with Zn) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, POTASSIUM ION, Potassium voltage-gated channel, ... | 著者 | Chi, G, Qian, P, Castro-Hartmann, P, Venkaya, S, Singh, N.K, McKinley, G, Mukhopadhyay, S.M.M, Fernandez-Cid, A, Marsden, B, MacLean, E.M, Pike, A.C.W, Sader, K, Burgess-Brown, N.A, Duerr, K.L. | 登録日 | 2021-08-17 | 公開日 | 2022-03-02 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain. Nat Commun, 13, 2022
|
|
7PHL
| Human voltage-gated potassium channel Kv3.1 (with EDTA) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, POTASSIUM ION, Potassium voltage-gated channel, ... | 著者 | Chi, G, Qian, P, Castro-Hartmann, P, Venkaya, S, Singh, N.K, McKinley, G, Mukhopadhyay, S.M.M, Fernandez-Cid, A, Pike, A.C.W, Marsden, B, MacLean, E.M, Sader, K, Burgess-Brown, N.A, Duerr, K.L. | 登録日 | 2021-08-17 | 公開日 | 2022-03-02 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain. Nat Commun, 13, 2022
|
|
7PHK
| Human voltage-gated potassium channel Kv3.1 in dimeric state (with Zn) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, POTASSIUM ION, Potassium voltage-gated channel, ... | 著者 | Chi, G, Qian, P, Castro-Hartmann, P, Venkaya, S, Singh, N.K, McKinley, G, Mukhopadhyay, S.M.M, Marsden, B, MacLean, E.M, Fernandez-Cid, A, Pike, A.C.W, Sader, K, Burgess-Brown, N.A, Duerr, K.L. | 登録日 | 2021-08-17 | 公開日 | 2022-03-02 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain. Nat Commun, 13, 2022
|
|
7PHH
| Human voltage-gated potassium channel Kv3.1 (apo condition) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, POTASSIUM ION, Potassium voltage-gated channel, ... | 著者 | Chi, G, Venkaya, S, Singh, N.K, McKinley, G, Mukhopadhyay, S.M.M, Marsden, B, MacLean, E.M, Fernandez-Cid, A, Pike, A.C.W, Savva, C, Ragan, T.J, Burgess-Brown, N.A, Duerr, K.L. | 登録日 | 2021-08-17 | 公開日 | 2022-03-02 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain. Nat Commun, 13, 2022
|
|
7RHS
| Cryo-EM structure of apo-state of human CNGA3/CNGB3 channel | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cyclic nucleotide-gated cation channel alpha-3, Cyclic nucleotide-gated cation channel beta-3, ... | 著者 | Zheng, X, Yang, J. | 登録日 | 2021-07-18 | 公開日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structure of the human cone photoreceptor cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 29, 2022
|
|
7TDK
| Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 3 (Dataset-A) | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ... | 著者 | Nayak, A.R, Samso, M. | 登録日 | 2021-12-31 | 公開日 | 2022-03-09 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM. Elife, 11, 2022
|
|
7TDH
| Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in open conformation | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ... | 著者 | Nayak, A.R, Samso, M. | 登録日 | 2021-12-31 | 公開日 | 2022-03-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM. Elife, 11, 2022
|
|
7TDI
| Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 2 (Dataset-A) | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ... | 著者 | Nayak, A.R, Samso, M. | 登録日 | 2021-12-31 | 公開日 | 2022-03-09 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM. Elife, 11, 2022
|
|
7TDG
| |
7TDJ
| Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 1(Dataset-A) | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ... | 著者 | Nayak, A.R, Samso, M. | 登録日 | 2021-12-31 | 公開日 | 2022-03-09 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM. Elife, 11, 2022
|
|
7N17
| Structure of TAX-4_R421W apo open state | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | 登録日 | 2021-05-27 | 公開日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
|
|
7N16
| Structure of TAX-4_R421W apo closed state | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, SODIUM ION | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | 登録日 | 2021-05-27 | 公開日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
|
|
7N15
| Structure of TAX-4_R421W w/cGMP open state | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | 登録日 | 2021-05-27 | 公開日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
|
|
7T3R
| IP3 and ATP bound type 3 IP3 receptor in the pre-active C state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
|
|
7T3P
| IP3 and ATP bound type 3 IP3 receptor in the pre-active A state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
|
|
7T3U
| IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the inactive state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
|
|
7T3Q
| IP3 and ATP bound type 3 IP3 receptor in the pre-active B state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
|
|
7T3T
| IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the active state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | 登録日 | 2021-12-08 | 公開日 | 2022-03-23 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
|
|