7WF3
Composite map of human Kv1.3 channel in apo state with beta subunits
Summary for 7WF3
Entry DOI | 10.2210/pdb7wf3/pdb |
EMDB information | 32459 |
Descriptor | Potassium voltage-gated channel subfamily A member 3, Voltage-gated potassium channel subunit beta-2, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | ion channel, kv channel, potassium channel, peptide toxin, shk, dalazatide, selectivity filter, molecular dynamics simulation, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 328047.86 |
Authors | Tyagi, A.,Ahmed, T.,Jian, S.,Bajaj, S.,Ong, S.T.,Goay, S.S.M.,Zhao, Y.,Vorobyov, I.,Tian, C.,Chandy, K.G.,Bhushan, S. (deposition date: 2021-12-25, release date: 2022-02-09, Last modification date: 2022-05-25) |
Primary citation | Tyagi, A.,Ahmed, T.,Jian, S.,Bajaj, S.,Ong, S.T.,Goay, S.S.M.,Zhao, Y.,Vorobyov, I.,Tian, C.,Chandy, K.G.,Bhushan, S. Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 35091471DOI: 10.1073/pnas.2113536119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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