7WF3
Composite map of human Kv1.3 channel in apo state with beta subunits
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005249 | molecular_function | voltage-gated potassium channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0008076 | cellular_component | voltage-gated potassium channel complex |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005249 | molecular_function | voltage-gated potassium channel activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006813 | biological_process | potassium ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005249 | molecular_function | voltage-gated potassium channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0006813 | biological_process | potassium ion transport |
| D | 0008076 | cellular_component | voltage-gated potassium channel complex |
| D | 0016020 | cellular_component | membrane |
| D | 0055085 | biological_process | transmembrane transport |
| F | 0005216 | molecular_function | monoatomic ion channel activity |
| F | 0005249 | molecular_function | voltage-gated potassium channel activity |
| F | 0006811 | biological_process | monoatomic ion transport |
| F | 0006813 | biological_process | potassium ion transport |
| F | 0008076 | cellular_component | voltage-gated potassium channel complex |
| F | 0016020 | cellular_component | membrane |
| F | 0055085 | biological_process | transmembrane transport |
| G | 0005249 | molecular_function | voltage-gated potassium channel activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006813 | biological_process | potassium ion transport |
| G | 0016020 | cellular_component | membrane |
| G | 0055085 | biological_process | transmembrane transport |
| H | 0005216 | molecular_function | monoatomic ion channel activity |
| H | 0005249 | molecular_function | voltage-gated potassium channel activity |
| H | 0006811 | biological_process | monoatomic ion transport |
| H | 0006813 | biological_process | potassium ion transport |
| H | 0008076 | cellular_component | voltage-gated potassium channel complex |
| H | 0016020 | cellular_component | membrane |
| H | 0055085 | biological_process | transmembrane transport |
| I | 0005249 | molecular_function | voltage-gated potassium channel activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0006813 | biological_process | potassium ion transport |
| I | 0016020 | cellular_component | membrane |
| I | 0055085 | biological_process | transmembrane transport |
| J | 0005249 | molecular_function | voltage-gated potassium channel activity |
| J | 0006813 | biological_process | potassium ion transport |
| J | 0008076 | cellular_component | voltage-gated potassium channel complex |
| J | 0051260 | biological_process | protein homooligomerization |
| M | 0005249 | molecular_function | voltage-gated potassium channel activity |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0006813 | biological_process | potassium ion transport |
| M | 0016020 | cellular_component | membrane |
| M | 0055085 | biological_process | transmembrane transport |
| N | 0005249 | molecular_function | voltage-gated potassium channel activity |
| N | 0006813 | biological_process | potassium ion transport |
| N | 0008076 | cellular_component | voltage-gated potassium channel complex |
| N | 0051260 | biological_process | protein homooligomerization |
| O | 0005249 | molecular_function | voltage-gated potassium channel activity |
| O | 0006813 | biological_process | potassium ion transport |
| O | 0008076 | cellular_component | voltage-gated potassium channel complex |
| O | 0051260 | biological_process | protein homooligomerization |
| P | 0005249 | molecular_function | voltage-gated potassium channel activity |
| P | 0006813 | biological_process | potassium ion transport |
| P | 0008076 | cellular_component | voltage-gated potassium channel complex |
| P | 0051260 | biological_process | protein homooligomerization |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 84 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 100 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 72 |
| Details | Transmembrane: {"description":"Helical; Voltage-sensor; Name=Segment S4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 76 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 160 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 88 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Motif: {"description":"Selectivity filter","evidences":[{"source":"UniProtKB","id":"P63142","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"P62483","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 76 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2005","submissionDatabase":"PDB data bank","title":"Crystal structure of human potassium channel Kv beta-subunit (KCNAB2).","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"1ZSX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P62483","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21357749","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
