7T3Q
IP3 and ATP bound type 3 IP3 receptor in the pre-active B state
This is a non-PDB format compatible entry.
Summary for 7T3Q
Entry DOI | 10.2210/pdb7t3q/pdb |
EMDB information | 25668 |
Descriptor | Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | ip3 receptor, calcium signaling, metal transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 1201274.24 |
Authors | Schmitz, E.A.,Takahashi, H.,Karakas, E. (deposition date: 2021-12-08, release date: 2022-03-23, Last modification date: 2022-05-04) |
Primary citation | Schmitz, E.A.,Takahashi, H.,Karakas, E. Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13:1408-1408, 2022 Cited by PubMed: 35301323DOI: 10.1038/s41467-022-29073-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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