7DXG

Structure of SAR7334-bound TRPC6 at 2.9 angstrom

Summary for 7DXG

Entry DOI	10.2210/pdb7dxg/pdb
EMDB information	30908
Descriptor	Short transient receptor potential channel 6, ZINC ION, CALCIUM ION, ... (7 entities in total)
Functional Keywords	trpc6, trpc, fsgs, sar7334, channel, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	441178.58
Authors	Chen, L.,Guo, W. (deposition date: 2021-01-18, release date: 2022-02-02, Last modification date: 2024-06-05)
Primary citation	Guo, W.,Tang, Q.,Wei, M.,Kang, Y.,Wu, J.X.,Chen, L. Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110:1023-1035.e5, 2022 Cited by PubMed: 35051376 DOI: 10.1016/j.neuron.2021.12.023 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation