7DXG
Structure of SAR7334-bound TRPC6 at 2.9 angstrom
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Short transient receptor potential channel 6 | polymer | 931 | 106453.2 | 4 | UniProt (Q9Y210) Pfam (PF12796) Pfam (PF08344) Pfam (PF00520) | Homo sapiens (human) | TrpC6,Transient receptor protein 6,TRP-6 |
| 2 | BA, E, KA, P (C, A, D, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | CA, F, FA, I, LA... (C, A, D, B) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) PubChem (271) | |||
| 4 | AA, DA, G, GA, IA... (C, A, D, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 16 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) | |||
| 5 | EA, H, NA, S (C, A, D, B) | 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile | non-polymer | 367.9 | 4 | Chemie (HOR) PubChem (53378752) PubChem (53378756) PubChem (76028597) PubChem (129407837) PubChem (134694116) | |||
| 6 | HA, K, QA, V (C, A, D, B) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 4 | Chemie (POV) PubChem (65167) PubChem (168614) PubChem (6070971) PubChem (5497103) PubChem (6436017) PubChem (6506401) PubChem (10908846) | |||
| 7 | M, O, X, Z (A, B) | [(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate | non-polymer | 621.0 | 4 | Chemie (98R) PubChem (162623415) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 425813.0 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 15365.6 | |
| All* | Total formula weight | 441178.6 |
