7DXG
Structure of SAR7334-bound TRPC6 at 2.9 angstrom
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Short transient receptor potential channel 6 | polymer | 931 | 106453.2 | 4 | UniProt (Q9Y210) Pfam (PF12796) Pfam (PF08344) Pfam (PF00520) Pfam (PF08016) In PDB | Homo sapiens (human) | TrpC6,Transient receptor protein 6,TRP-6 |
2 | C, A, D, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | C, A, D, B | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
4 | C, A, D, B | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 16 | Chemie (Y01) | |||
5 | C, A, D, B | 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile | non-polymer | 367.9 | 4 | Chemie (HOR) | |||
6 | C, A, D, B | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 4 | Chemie (POV) | |||
7 | A, B | [(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate | non-polymer | 621.0 | 4 | Chemie (98R) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 425813.0 | |
Non-Polymers* | Number of molecules | 40 |
Total formula weight | 15365.6 | |
All* | Total formula weight | 441178.6 |