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7DXG

Structure of SAR7334-bound TRPC6 at 2.9 angstrom

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DShort transient receptor potential channel 6polymer931106453.24UniProt (Q9Y210)
Pfam (PF12796)
Pfam (PF08344)
Pfam (PF00520)
Pfam (PF08016)
In PDB
Homo sapiens (human)TrpC6,Transient receptor protein 6,TRP-6
2C, A, D, BZINC IONnon-polymer65.44Chemie (ZN)
3C, A, D, BCALCIUM IONnon-polymer40.18Chemie (CA)
4C, A, D, BCHOLESTEROL HEMISUCCINATEnon-polymer486.716Chemie (Y01)
5C, A, D, B4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrilenon-polymer367.94Chemie (HOR)
6C, A, D, B(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.14Chemie (POV)
7A, B[(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoatenon-polymer621.04Chemie (98R)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight425813.0
Non-Polymers*Number of molecules40
Total formula weight15365.6
All*Total formula weight441178.6
*Water molecules are not included.

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PDB entries from 2024-08-07

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