7TDK

Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 3 (Dataset-A)

This is a non-PDB format compatible entry.

Summary for 7TDK

• Entry DOI: 10.2210/pdb7tdk/pdb
• Related: 7K0T 7TDG 7TDH 7TDI 7TDJ
• EMDB information: 25832 25833
• Descriptor: Ryanodine receptor 1,Ryanodine receptor 1,RyR1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ZINC ION, ... (4 entities in total)
• Functional Keywords: ryanodine receptor, ryr1, intracellular calcium channel, ca2+, inactivation, excitation-contraction coupling, transport protein
• Biological source: Oryctolagus cuniculus (rabbit); More
• Total number of polymer chains: 4
• Total formula weight: 2137256.09

Authors

Nayak, A.R.,Samso, M. (deposition date: 2021-12-31, release date: 2022-03-09, Last modification date: 2022-03-16)

• Primary citation: Nayak, A.R.,Samso, M.; Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.; Elife, 11:-, 2022; PubMed: 35257661; DOI: 10.7554/eLife.75568

Experimental method

ELECTRON MICROSCOPY (3.8 Å)