PDB: 10530 件ウェブページステータス検索Chemie searchBIRD

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3E79	Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37 分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Sippel, K.H, Robbins, A.H, Reutzel, R, Domsic, J, McKenna, R. 登録日 2008-08-18 公開日 2008-10-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37. Acta Crystallogr.,Sect.D, 64, 2008
3EM3	Crystal structure of amprenavir (APV) in complex with a drug resistant HIV-1 protease variant (I50L/A71V). 分子名称: ACETATE ION, Protease, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER 著者 Prabu-Jeyabalan, M, King, N, Royer, C, Schiffer, C. 登録日 2008-09-23 公開日 2009-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Kinetic and Structural Studies on Atazanavir-specific I50L Drug-Resistant HIV-1 Protease Mutant To be Published
3FTU	Leukotriene A4 hydrolase in complex with dihydroresveratrol 分子名称: 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol, ACETATE ION, IMIDAZOLE, ... 著者 Davies, D.R. 登録日 2009-01-13 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FSI	Crystal structure of a trypanocidal 4,4'-Bis(imidazolinylamino)diphenylamine bound to DNA 分子名称: 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', ACETATE ION, ... 著者 Glass, L.S, Georgiadis, M.M, Goodwin, K.D. 登録日 2009-01-09 公開日 2009-05-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA. Biochemistry, 48, 2009
3EPF	CryoEM structure of poliovirus receptor bound to poliovirus type 2 分子名称: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, Poliovirus receptor, ... 著者 Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G. 登録日 2008-09-29 公開日 2008-11-11 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses. Proc.Natl.Acad.Sci.USA, 105, 2008
3E9Y	Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron 分子名称: 2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ... 著者 Guddat, L.W, Duggleby, R.G, Wang, J.-G, Li, Z.-M. 登録日 2008-08-24 公開日 2009-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. Febs J., 276, 2009
3H3C	Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog 分子名称: 4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide, Protein tyrosine kinase 2 beta, SULFATE ION 著者 Han, S, Mistry, A. 登録日 2009-04-16 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity. Bioorg.Med.Chem.Lett., 19, 2009
3CKT	HIV-1 protease in complex with a dimethylallyl decorated pyrrolidine based inhibitor (orthorombic space group) 分子名称: (3S,4S),-3,4-Bis-[(4-carbamoyl-benzensulfonyl)-(3-methyl-but-2-enyl)-amino]-pyrrolidine, CHLORIDE ION, Protease 著者 Boettcher, J, Blum, A, Heine, A, Diederich, W.E, Klebe, G. 登録日 2008-03-17 公開日 2009-03-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Two Solutions for the Same Problem: Multiple Binding Modes of Pyrrolidine-Based HIV-1 Protease Inhibitors J.Mol.Biol., 410, 2011
3CIC	Structure of BACE Bound to SCH709583 分子名称: Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2S)-2-[(2S)-4-benzyl-3-oxopiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide 著者 Strickland, C, Cumming, J. 登録日 2008-03-11 公開日 2008-06-10 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors Bioorg.Med.Chem.Lett., 18, 2008
3GT4	Structure of proteinase K with the magic triangle I3C 分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, SULFATE ION, proteinase K 著者 Beck, T, Gruene, T, Sheldrick, G.M. 登録日 2009-03-27 公開日 2009-04-14 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 The magic triangle goes MAD: experimental phasing with a bromine derivative Acta Crystallogr.,Sect.D, 66, 2010
3GT3	Structure of proteinase K with the mad triangle B3C 分子名称: 5-amino-2,4,6-tribromobenzene-1,3-dicarboxylic acid, Proteinase K, SULFATE ION 著者 Beck, T, Gruene, T, Sheldrick, G.M. 登録日 2009-03-27 公開日 2009-04-14 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The magic triangle goes MAD: experimental phasing with a bromine derivative Acta Crystallogr.,Sect.D, 66, 2010
5XLZ	The crystal structure of tubulin complexed with a benzylidene derivative of 9(10H)-anthracenone 分子名称: 10-[(4-methoxy-3-oxidanyl-phenyl)methylidene]anthracen-9-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Yu, Y, Chen, Q. 登録日 2017-05-12 公開日 2017-11-22 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Structure of a benzylidene derivative of 9(10H)-anthracenone in complex with tubulin provides a rationale for drug design. Biochem. Biophys. Res. Commun., 495, 2018
5Y4S	Structure of a methyltransferase complex 分子名称: Chemotaxis protein methyltransferase 1 著者 Yan, X, Xin, L, Tan, Y.J, Jin, S, Liang, Z.X, Gao, Y.G. 登録日 2017-08-04 公開日 2017-11-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.405 Å) 主引用文献 Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein. J. Biol. Chem., 293, 2018
5YE2	mammalian endo-lysosomal TRPML1 channel inserting into amphipol 分子名称: mammalian endo-lysosomal TRPML1 channel 著者 Yang, M, Gao, N. 登録日 2017-09-15 公開日 2017-12-27 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8, 2017
5YEV	Murine DR3 death domain 分子名称: SULFATE ION, TNFRSF25 death domain 著者 Yin, X, Jin, T. 登録日 2017-09-19 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
5YE1	structure of endo-lysosomal TRPML1 channel inserting into amphipol: state 2 分子名称: Mucolipin-1 著者 Yang, M, Gao, N. 登録日 2017-09-15 公開日 2017-12-27 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8, 2017
5YGP	Human TNFRSF25 death domain mutant-D412E 分子名称: SULFATE ION, TNFRSF25 death domain, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Yin, X, Jin, T.C. 登録日 2017-09-25 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
5XXY	Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A 分子名称: Programmed cell death 1 ligand 1, heavy chain of atezolizumab fab, light chain of atezolizumab fab 著者 Zhou, A, Zhang, F. 登録日 2017-07-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab. Oncotarget, 8, 2017
5Y4R	Structure of a methyltransferase complex 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Chemotaxis protein methyltransferase 1, Cyclic diguanosine monophosphate-binding protein PA4608, ... 著者 Yan, X, Xin, L, Tan, Y.J, Jin, S, Liang, Z.X, Gao, Y.G. 登録日 2017-08-04 公開日 2017-11-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein. J. Biol. Chem., 293, 2018
5WUD	Structural basis for conductance through TRIC cation channels 分子名称: MAGNESIUM ION, Uncharacterized protein 著者 Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2016-12-17 公開日 2017-06-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for conductance through TRIC cation channels. Nat Commun, 8, 2017
5YI8	Crystal structure of drosophila Numb PTB domain and Pon peptide complex 分子名称: FORMIC ACID, Pon peptide from Partner of numb, Protein numb 著者 Shan, Z, Wen, W. 登録日 2017-10-03 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nat Commun, 9, 2018
5YD0	Crystal structure of Schlafen 13 (SLFN13) N'-domain 分子名称: Schlafen 8, ZINC ION 著者 Yang, J.-Y, Gao, S. 登録日 2017-09-09 公開日 2018-03-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.182 Å) 主引用文献 Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control Nat Commun, 9, 2018
5YKF	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-10-14 公開日 2018-04-18 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.33 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5WT1	Pyrococcus abyssi methyltransferase PaTrm5a bound by SAH and cognate tRNA 分子名称: RNA (76-MER), S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine(37)-N1)-methyltransferase Trm5a 著者 Xie, W, Wang, C, Jia, Q. 登録日 2016-12-09 公開日 2017-12-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.598 Å) 主引用文献 Structural insight into the methyltransfer mechanism of the bifunctional Trm5. Sci Adv, 3, 2017
5WPQ	Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed I conformation at 3.64 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION 著者 Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. 登録日 2017-08-07 公開日 2017-10-18 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structure of mammalian endolysosomal TRPML1 channel in nanodiscs. Nature, 550, 2017

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