6GVY
 
 | |
1ONM
 | | Solution Structure of a DNA duplex containing A:G mismatch. d(GCTTCAGTCGT):d(ACGACGGAAGC) | | 分子名称: | 5'-D(*AP*CP*GP*AP*CP*GP*GP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*CP*AP*GP*TP*CP*GP*T)-3' | | 著者 | Sanchez, A.M, Volk, D.E, Gorenstein, D.G, Lloyd, R.S. | | 登録日 | 2003-02-28 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Initiation of repair of A/G mismatches is modulated by sequence context
DNA REPAIR, 2, 2003
|
|
6S5A
 | | CRYSTAL STRUCTURE OF FC P329G LALA WITH ANTI FC P329G FAB | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc P329G LALA, ... | | 著者 | Ehler, A, Darowski, D, Jost, C, Stubenrauch, K, Wessels, U, Benz, J, Birk, M, Freimoser-Grundschober, A, Bruenker, P, Moessner, E, Umana, P, Kobold, S, Klein, C. | | 登録日 | 2019-07-01 | | 公開日 | 2019-09-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation.
Protein Eng.Des.Sel., 32, 2019
|
|
5KJE
 | | F322L horse liver alcohol dehydrogenase complexed with NAD+ and pentafluorobenzyl alcohol | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | | 著者 | Plapp, B.V. | | 登録日 | 2016-06-18 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Contribution of buried distal amino acid residues in horse liver alcohol dehydrogenase to structure and catalysis.
Protein Sci., 27, 2018
|
|
5KMT
 | | CTX-M9 mutant L48A | | 分子名称: | Beta-lactamase, PHOSPHATE ION, POTASSIUM ION | | 著者 | Latallo, M.J, Faham, S, Kasson, P.M. | | 登録日 | 2016-06-27 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme.
Chem Sci, 8, 2017
|
|
6RT3
 | | Native tetragonal lysozyme - synchrotron data | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | | 著者 | Pereira, P.J.B. | | 登録日 | 2019-05-22 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Protein crystals as a key for deciphering macromolecular crowding effects on biological reactions.
Phys Chem Chem Phys, 22, 2020
|
|
6GP5
 | | Beta-1,4-galactanase from Bacteroides thetaiotaomicron | | 分子名称: | Arabinogalactan endo-beta-1,4-galactanase | | 著者 | Hekelaar, J, Boger, M, Leeuwen van, S.S, Lammerts van Bueren, A, Dijkhuizen, L. | | 登録日 | 2018-06-05 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural and functional characterization of a family GH53 beta-1,4-galactanase from Bacteroides thetaiotaomicron that facilitates degradation of prebiotic galactooligosaccharides.
J. Struct. Biol., 205, 2019
|
|
6TZG
 | | ADC-7 in complex with boronic acid transition state inhibitor S17083 | | 分子名称: | Beta-lactamase, [4-(3-aminocarbonylphenyl)-1,2,3-triazol-1-yl]methyl-phosphonooxy-borinic acid | | 著者 | Fish, E.R, Powers, R.A, Wallar, B.J. | | 登録日 | 2019-08-12 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.816 Å) | | 主引用文献 | 1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of beta-Lactamase Inhibitors againstAcinetobacter baumanniiCephalosporinase.
Acs Infect Dis., 6, 2020
|
|
6U4V
 | | Non-crosslinked wild type cysteine dioxygenase | | 分子名称: | Cysteine dioxygenase type 1, FE (III) ION | | 著者 | Meneely, K.M, Chilton, A.S, Forbes, D.L, Ellis, H.R, Lamb, A.L. | | 登録日 | 2019-08-26 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The 3-His Metal Coordination Site Promotes the Coupling of Oxygen Activation to Cysteine Oxidation in Cysteine Dioxygenase.
Biochemistry, 59, 2020
|
|
6E65
 | |
6U97
 | | Structure of OmcF_H47I mutant | | 分子名称: | Lipoprotein cytochrome c, 1 heme-binding site, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Pokkuluri, P.R. | | 登録日 | 2019-09-06 | | 公開日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Modulation of the Redox Potential and Electron/Proton Transfer Mechanisms in the Outer Membrane Cytochrome OmcF FromGeobacter sulfurreducens.
Front Microbiol, 10, 2019
|
|
6EF6
 | |
6UFB
 | |
1OZ9
 | | Crystal structure of AQ_1354, a hypothetical protein from Aquifex aeolicus | | 分子名称: | Hypothetical protein AQ_1354 | | 著者 | Oganesyan, V, Busso, D, Brandsen, J, Chen, S, Jancarik, J, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2003-04-08 | | 公開日 | 2003-09-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.894 Å) | | 主引用文献 | Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
6EKU
 | | Vibrio cholerae neuraminidase complexed with zanamivir | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Schuetz, A, Heinemann, U. | | 登録日 | 2017-09-27 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Different Inhibitory Potencies of Oseltamivir Carboxylate, Zanamivir, and Several Tannins on Bacterial and Viral Neuraminidases as Assessed in a Cell-Free Fluorescence-Based Enzyme Inhibition Assay.
Molecules, 22, 2017
|
|
6U7N
 | | Crystal structure of neurotrimin (NTM) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Neurotrimin, ... | | 著者 | Machius, M, Venkannagari, H, Misra, A, Rudenko, G, Rush, S. | | 登録日 | 2019-09-03 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.321 Å) | | 主引用文献 | Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
J.Mol.Biol., 432, 2020
|
|
6GPA
 | | Beta-1,4-galactanase from Bacteroides thetaiotaomicron with galactose | | 分子名称: | Arabinogalactan endo-beta-1,4-galactanase, beta-D-galactopyranose | | 著者 | Hekelaar, J, Boger, M, Leeuwen van, S.S, Lammerts van Bueren, A, Dijkhuizen, L. | | 登録日 | 2018-06-05 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural and functional characterization of a family GH53 beta-1,4-galactanase from Bacteroides thetaiotaomicron that facilitates degradation of prebiotic galactooligosaccharides.
J. Struct. Biol., 205, 2019
|
|
6H23
 | | Crystal structure of the hClpP Y118A mutant with an activating small molecule | | 分子名称: | 1,2-ETHANEDIOL, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... | | 著者 | Kick, L.M, Sieber, S.A, Schneider, S. | | 登録日 | 2018-07-13 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.089 Å) | | 主引用文献 | Selective Activation of Human Caseinolytic Protease P (ClpP).
Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
1Q78
 | | Crystal structure of poly(A) polymerase in complex with 3'-dATP and magnesium chloride | | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Poly(A) polymerase alpha | | 著者 | Martin, G, Moglich, A, Keller, W, Doublie, S. | | 登録日 | 2003-08-16 | | 公開日 | 2004-09-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase.
J.Mol.Biol., 341, 2004
|
|
1PZI
 | | Heat-Labile Enterotoxin B-Pentamer Complexed With Nitrophenyl Galactoside 2a | | 分子名称: | Heat-labile Enterotoxin B subunit, N-(2-MORPHOLIN-4-YL-1-MORPHOLIN-4-YLMETHYL-ETHYL)-3-NITRO-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE | | 著者 | Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J. | | 登録日 | 2003-07-11 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
|
|
1Q79
 | | CRYSTAL STRUCTURE OF MAMMALIAN POLY(A) POLYMERASE | | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Martin, G, Moglich, A, Keller, W, Doublie, S. | | 登録日 | 2003-08-16 | | 公開日 | 2004-09-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase.
J.Mol.Biol., 341, 2004
|
|
1Q9B
 | |
1OF1
 | | KINETICS AND CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (SOUTH)-METHANOCARBA-THYMIDINE | | 分子名称: | (SOUTH)-METHANOCARBA-THYMIDINE, SULFATE ION, THYMIDINE KINASE | | 著者 | Claus, M.T, Schelling, P, Folkers, G, Marquez, V.E, Scapozza, L, Schulz, G.E. | | 登録日 | 2003-04-03 | | 公開日 | 2004-06-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Biochemical and Structural Characterization of (South)-Methanocarbathymidine that Specifically Inhibits Growth of Herpes Simplex Virus Type 1 Thymidine Kinase-Transduced Osteosarcoma Cells
J.Biol.Chem., 279, 2004
|
|
1PWD
 | | Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C | | 分子名称: | (2R)-5-(acetyloxymethyl)-2-[(1R)-1-[[(5R)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase precursor | | 著者 | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | | 登録日 | 2003-07-01 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
|
|
1PXX
 | | CRYSTAL STRUCTURE OF DICLOFENAC BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2 | | 分子名称: | 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kiefer, J.R, Rowlinson, S.W, Prusakiewicz, J.J, Pawlitz, J.L, Kozak, K.R, Kalgutkar, A.S, Stallings, W.C, Marnett, L.J, Kurumbail, R.G. | | 登録日 | 2003-07-07 | | 公開日 | 2003-09-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385.
J.Biol.Chem., 278, 2003
|
|
