6S5A

CRYSTAL STRUCTURE OF FC P329G LALA WITH ANTI FC P329G FAB

Summary for 6S5A

Entry DOI	10.2210/pdb6s5a/pdb
Descriptor	Fc P329G LALA, anti P329G LALA Fab heavy chain, anti P329G LALA Fab light chain, ... (8 entities in total)
Functional Keywords	antibody, fc, p329g lala, fab, anti p329g lala fab, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	103631.78
Authors	Ehler, A.,Darowski, D.,Jost, C.,Stubenrauch, K.,Wessels, U.,Benz, J.,Birk, M.,Freimoser-Grundschober, A.,Bruenker, P.,Moessner, E.,Umana, P.,Kobold, S.,Klein, C. (deposition date: 2019-07-01, release date: 2019-09-25, Last modification date: 2020-07-29)
Primary citation	Darowski, D.,Jost, C.,Stubenrauch, K.,Wessels, U.,Benz, J.,Ehler, A.,Freimoser-Grundschober, A.,Brunker, P.,Mossner, E.,Umana, P.,Kobold, S.,Klein, C. P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation. Protein Eng.Des.Sel., 32:207-218, 2019 Cited by PubMed: 31504896 DOI: 10.1093/protein/gzz027 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation