8RDJ
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![BU of 8rdj by Molmil](/molmil-images/mine/8rdj) | Plastid-encoded RNA polymerase transcription elongation complex (Integrated model) | 分子名称: | DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | 登録日 | 2023-12-08 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | Structure of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
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6PO2
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![BU of 6po2 by Molmil](/molmil-images/mine/6po2) | In situ structure of BTV RNA-dependent RNA polymerase in BTV core | 分子名称: | Inner core structural protein VP3, RNA-directed RNA polymerase | 著者 | He, Y, Shivakoti, S, Ding, K, Cui, Y, Roy, P, Zhou, Z.H. | 登録日 | 2019-07-03 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proc.Natl.Acad.Sci.USA, 116, 2019
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6PNS
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![BU of 6pns by Molmil](/molmil-images/mine/6pns) | In situ structure of BTV RNA-dependent RNA polymerase in BTV virion | 分子名称: | Inner core structural protein VP3, RNA-directed RNA polymerase | 著者 | He, Y, Shivakoti, S, Ding, K, Cui, Y, Roy, P, Zhou, Z.H. | 登録日 | 2019-07-03 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proc.Natl.Acad.Sci.USA, 116, 2019
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6BYU
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![BU of 6byu by Molmil](/molmil-images/mine/6byu) | X-ray crystal structure of Escherichia coli RNA polymerase (RpoB-H526Y) and ppApp complex | 分子名称: | (5R)-5-(6-amino-9H-purin-9-yl)-2-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}methyl)-4-oxo-4,5-dihydrofuran-3-yl trihydrogen diphosphate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Murakami, K.S, Molodtsov, V. | 登録日 | 2017-12-21 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro. Biochim. Biophys. Acta, 1861, 2018
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2D7S
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![BU of 2d7s by Molmil](/molmil-images/mine/2d7s) | Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein | 分子名称: | RNA-dependent RNA polymerase, VPg1 protein | 著者 | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | 登録日 | 2005-11-29 | 公開日 | 2006-03-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
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3AYH
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![BU of 3ayh by Molmil](/molmil-images/mine/3ayh) | |
8G4W
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![BU of 8g4w by Molmil](/molmil-images/mine/8g4w) | Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand | 分子名称: | 7-DEAZA-7-AMINOMETHYL-GUANINE, DNA (31-MER), DNA (39-mer), ... | 著者 | Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. | 登録日 | 2023-02-10 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
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4KMU
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![BU of 4kmu by Molmil](/molmil-images/mine/4kmu) | |
3HKZ
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![BU of 3hkz by Molmil](/molmil-images/mine/3hkz) | |
4KN4
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![BU of 4kn4 by Molmil](/molmil-images/mine/4kn4) | |
4KN7
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![BU of 4kn7 by Molmil](/molmil-images/mine/4kn7) | |
7ZF2
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![BU of 7zf2 by Molmil](/molmil-images/mine/7zf2) | Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. | 登録日 | 2022-03-31 | 公開日 | 2023-02-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization. Nat Commun, 14, 2023
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7B7U
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![BU of 7b7u by Molmil](/molmil-images/mine/7b7u) | Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Fianu, I, Dienemann, C, Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2020-12-11 | 公開日 | 2021-05-19 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2. Commun Biol, 4, 2021
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7BTF
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![BU of 7btf by Molmil](/molmil-images/mine/7btf) | SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-04-01 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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2GHO
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8RBO
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![BU of 8rbo by Molmil](/molmil-images/mine/8rbo) | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation | 分子名称: | DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... | 著者 | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | 登録日 | 2023-12-04 | 公開日 | 2024-04-24 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
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6M71
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![BU of 6m71 by Molmil](/molmil-images/mine/6m71) | SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-03-16 | 公開日 | 2020-04-01 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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3MMP
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![BU of 3mmp by Molmil](/molmil-images/mine/3mmp) | Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins | 分子名称: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... | 著者 | Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. | 登録日 | 2010-04-20 | 公開日 | 2010-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins. Proc.Natl.Acad.Sci.USA, 107, 2010
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4JKR
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![BU of 4jkr by Molmil](/molmil-images/mine/4jkr) | Crystal Structure of E. coli RNA Polymerase in complex with ppGpp | 分子名称: | DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, Wang, Y, Steitz, T.A. | 登録日 | 2013-03-11 | 公開日 | 2013-05-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex. Mol.Cell, 50, 2013
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2CW0
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![BU of 2cw0 by Molmil](/molmil-images/mine/2cw0) | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark Jr, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | 登録日 | 2005-06-15 | 公開日 | 2005-09-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation Cell(Cambridge,Mass.), 122, 2005
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4QIW
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![BU of 4qiw by Molmil](/molmil-images/mine/4qiw) | |
8QMA
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![BU of 8qma by Molmil](/molmil-images/mine/8qma) | Structure of the plastid-encoded RNA polymerase complex (PEP) from Sinapis alba | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | do Prado, P.F.V, Ahrens, F.M, Pfannschmidt, T, Hillen, H.S. | 登録日 | 2023-09-21 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the multi-subunit chloroplast RNA polymerase. Mol.Cell, 84, 2024
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7OGR
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![BU of 7ogr by Molmil](/molmil-images/mine/7ogr) | Structure of the apo-state of the bacteriophage PhiKZ non-virion RNA polymerase | 分子名称: | DNA-directed RNA polymerase, PHIKZ055, PHIKZ068, ... | 著者 | de Martin Garrido, N, Lai Wan Loong, Y.T.E, Yakunina, M, Aylett, C.H.S. | 登録日 | 2021-05-07 | 公開日 | 2021-07-07 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the bacteriophage PhiKZ non-virion RNA polymerase. Nucleic Acids Res., 49, 2021
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1ZYR
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![BU of 1zyr by Molmil](/molmil-images/mine/1zyr) | Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ... | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | 登録日 | 2005-06-10 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation. Cell(Cambridge,Mass.), 122, 2005
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7OGP
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![BU of 7ogp by Molmil](/molmil-images/mine/7ogp) | Structure of the apo-state of the bacteriophage PhiKZ non-virion RNA polymerase - class including clamp | 分子名称: | DNA-directed RNA polymerase, PHIKZ055, PHIKZ068, ... | 著者 | de Martin Garrido, N, Lai Wan Loong, Y.T.E, Yakunina, M, Aylett, C.H.S. | 登録日 | 2021-05-07 | 公開日 | 2021-07-07 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the bacteriophage PhiKZ non-virion RNA polymerase. Nucleic Acids Res., 49, 2021
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