6GQV
| Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | 登録日 | 2018-06-08 | 公開日 | 2018-07-11 | 最終更新日 | 2018-08-08 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
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6GXN
| Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State III) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N. | 登録日 | 2018-06-27 | 公開日 | 2018-08-15 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nat Commun, 9, 2018
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6GAW
| Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome. | 分子名称: | 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ... | 著者 | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | 登録日 | 2018-04-13 | 公開日 | 2018-08-22 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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6GSM
| Structure of a partial yeast 48S preinitiation complex in open conformation. | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | 著者 | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | 登録日 | 2018-06-14 | 公開日 | 2019-07-31 | 最終更新日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Large-scale movement of eIF3 domains during translation initiation modulate start codon selection. Nucleic Acids Res., 2021
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5MQF
| Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... | 著者 | Bertram, K, Hartmuth, K, Kastner, B. | 登録日 | 2016-12-20 | 公開日 | 2017-03-22 | 最終更新日 | 2018-11-21 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542, 2017
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5ME1
| Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112 | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | 登録日 | 2016-11-14 | 公開日 | 2017-01-11 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | 主引用文献 | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways. Nucleic Acids Res., 45, 2017
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5MI3
| Structure of phosphorylated translation elongation factor EF-Tu from E. coli | 分子名称: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A. | 登録日 | 2016-11-27 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors. Sci Adv, 4, 2018
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5MPS
| Structure of a spliceosome remodeled for exon ligation | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | 登録日 | 2016-12-18 | 公開日 | 2017-01-18 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
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5MQ0
| Structure of a spliceosome remodeled for exon ligation | 分子名称: | 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | 登録日 | 2016-12-19 | 公開日 | 2017-01-18 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
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5NRL
| Structure of a pre-catalytic spliceosome. | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | 著者 | Plaschka, C, Lin, P.-C, Nagai, K. | 登録日 | 2017-04-24 | 公開日 | 2017-05-31 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Structure of a pre-catalytic spliceosome. Nature, 546, 2017
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5LZS
| Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B | 分子名称: | (2~{S})-~{N}-[(2~{R})-1-[[(3~{S},6~{S},8~{S},12~{S},13~{R},16~{S},17~{R},20~{S},23~{S})-13-[(2~{S})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-1-[(2~{S})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide, 18S ribosomal RNA, 28S ribosomal RNA, ... | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2016-10-02 | 公開日 | 2016-11-30 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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5LZX
| Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2016-10-02 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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5LZB
| Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the initial binding state (IB) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. | 登録日 | 2016-09-29 | 公開日 | 2016-11-23 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature, 540, 2016
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5M1J
| Nonstop ribosomal complex bound with Dom34 and Hbs1 | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. | 登録日 | 2016-10-07 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution. Nat Commun, 7, 2016
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5O9Z
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3J9Y
| Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Arenz, S, Nguyen, F, Beckmann, R, Wilson, D.N. | 登録日 | 2015-03-23 | 公開日 | 2015-04-15 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9- angstrom resolution. Proc.Natl.Acad.Sci.USA, 112, 2015
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3JCR
| 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | 分子名称: | LSm2, LSm3, LSm4, ... | 著者 | Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. | 登録日 | 2016-01-21 | 公開日 | 2016-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Molecular architecture of the human U4/U6.U5 tri-snRNP. Science, 351, 2016
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3JCE
| Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4) | 分子名称: | 16S ribosomal RNA, 23 ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y. | 登録日 | 2015-12-01 | 公開日 | 2016-01-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome Nat. Struct. Mol. Biol., 23, 2016
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3J81
| CryoEM structure of a partial yeast 48S preinitiation complex | 分子名称: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | 著者 | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | 登録日 | 2014-08-29 | 公開日 | 2014-11-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
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3IZP
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3IZY
| Mammalian mitochondrial translation initiation factor 2 | 分子名称: | Translation initiation factor IF-2, mitochondrial, tRNA-Phe | 著者 | Yassin, A.S, Haque, E, Datta, P.P, Elmore, K, Banavali, N.K, Spremulli, L.L, Agrawal, R.K. | 登録日 | 2011-01-19 | 公開日 | 2011-03-23 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (10.8 Å) | 主引用文献 | Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1 Proc.Natl.Acad.Sci.USA, 108, 2011
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5O8W
| CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | 分子名称: | Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ... | 著者 | Wirth, C, Andersen, G.R, Hunte, C. | 登録日 | 2017-06-14 | 公開日 | 2017-08-23 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A. J. Biol. Chem., 292, 2017
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3J5Y
| Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP | 分子名称: | 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ... | 著者 | des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2013-11-21 | 公開日 | 2013-12-25 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP. Nucleic Acids Res., 42, 2014
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5LZD
| Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. | 登録日 | 2016-09-29 | 公開日 | 2016-11-23 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature, 540, 2016
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5LZT
| Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2016-10-02 | 公開日 | 2016-11-30 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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