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6GQV
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Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y.
登録日2018-06-08
公開日2018-07-11
最終更新日2018-08-08
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6GXN
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Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State III)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
登録日2018-06-27
公開日2018-08-15
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GAW
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Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome.
分子名称: 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ...
著者Kummer, E, Leibundgut, M, Boehringer, D, Ban, N.
登録日2018-04-13
公開日2018-08-22
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Nature, 560, 2018
6GSM
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Structure of a partial yeast 48S preinitiation complex in open conformation.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
著者Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
登録日2018-06-14
公開日2019-07-31
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
5MQF
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Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ...
著者Bertram, K, Hartmuth, K, Kastner, B.
登録日2016-12-20
公開日2017-03-22
最終更新日2018-11-21
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature, 542, 2017
5ME1
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Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S.
登録日2016-11-14
公開日2017-01-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
5MI3
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Structure of phosphorylated translation elongation factor EF-Tu from E. coli
分子名称: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
登録日2016-11-27
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MPS
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Structure of a spliceosome remodeled for exon ligation
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
登録日2016-12-18
公開日2017-01-18
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MQ0
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Structure of a spliceosome remodeled for exon ligation
分子名称: 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ...
著者Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
登録日2016-12-19
公開日2017-01-18
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5NRL
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BU of 5nrl by Molmil
Structure of a pre-catalytic spliceosome.
分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
著者Plaschka, C, Lin, P.-C, Nagai, K.
登録日2017-04-24
公開日2017-05-31
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
5LZS
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Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
分子名称: (2~{S})-~{N}-[(2~{R})-1-[[(3~{S},6~{S},8~{S},12~{S},13~{R},16~{S},17~{R},20~{S},23~{S})-13-[(2~{S})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-1-[(2~{S})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide, 18S ribosomal RNA, 28S ribosomal RNA, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZX
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BU of 5lzx by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZB
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BU of 5lzb by Molmil
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the initial binding state (IB)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
5M1J
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BU of 5m1j by Molmil
Nonstop ribosomal complex bound with Dom34 and Hbs1
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
登録日2016-10-07
公開日2017-01-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
Nat Commun, 7, 2016
5O9Z
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Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
著者Bertram, K, Kastner, B.
登録日2017-06-20
公開日2017-08-16
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
3J9Y
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BU of 3j9y by Molmil
Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Arenz, S, Nguyen, F, Beckmann, R, Wilson, D.N.
登録日2015-03-23
公開日2015-04-15
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9- angstrom resolution.
Proc.Natl.Acad.Sci.USA, 112, 2015
3JCR
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BU of 3jcr by Molmil
3D structure determination of the human*U4/U6.U5* tri-snRNP complex
分子名称: LSm2, LSm3, LSm4, ...
著者Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H.
登録日2016-01-21
公開日2016-03-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Molecular architecture of the human U4/U6.U5 tri-snRNP.
Science, 351, 2016
3JCE
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BU of 3jce by Molmil
Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4)
分子名称: 16S ribosomal RNA, 23 ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
3J81
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BU of 3j81 by Molmil
CryoEM structure of a partial yeast 48S preinitiation complex
分子名称: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
著者Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V.
登録日2014-08-29
公開日2014-11-05
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3IZP
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BU of 3izp by Molmil
Conformation of EF-G during translocation
分子名称: Elongation factor G
著者Li, W, Trabuco, L.G, Schulten, K, Frank, J.
登録日2010-11-15
公開日2011-03-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY
主引用文献Molecular dynamics of EF-G during translocation.
Proteins, 79, 2011
3IZY
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BU of 3izy by Molmil
Mammalian mitochondrial translation initiation factor 2
分子名称: Translation initiation factor IF-2, mitochondrial, tRNA-Phe
著者Yassin, A.S, Haque, E, Datta, P.P, Elmore, K, Banavali, N.K, Spremulli, L.L, Agrawal, R.K.
登録日2011-01-19
公開日2011-03-23
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (10.8 Å)
主引用文献Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1
Proc.Natl.Acad.Sci.USA, 108, 2011
5O8W
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BU of 5o8w by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
分子名称: Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ...
著者Wirth, C, Andersen, G.R, Hunte, C.
登録日2017-06-14
公開日2017-08-23
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
3J5Y
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BU of 3j5y by Molmil
Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
分子名称: 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ...
著者des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2013-11-21
公開日2013-12-25
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
5LZD
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BU of 5lzd by Molmil
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
5LZT
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BU of 5lzt by Molmil
Structure of the mammalian ribosomal termination complex with eRF1 and eRF3.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016

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