7SHM
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7P06
| Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in outward-facing conformation with ADP-orthovanadate/ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ... | 著者 | Szewczak-Harris, A, Wagner, M, Du, D, Schmitt, L, Luisi, B.F. | 登録日 | 2021-06-29 | 公開日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5. Nat Commun, 12, 2021
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7P05
| Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in inward-facing conformation with ADP/ATP and rhodamine 6G | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Pleiotropic ABC efflux transporter of multiple drugs, ... | 著者 | Szewczak-Harris, A, Wagner, M, Du, D, Schmitt, L, Luisi, B.F. | 登録日 | 2021-06-29 | 公開日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5. Nat Commun, 12, 2021
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7P04
| Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in inward-facing conformation with ADP/ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Pleiotropic ABC efflux transporter of multiple drugs | 著者 | Szewczak-Harris, A, Wagner, M, Du, D, Schmitt, L, Luisi, B.F. | 登録日 | 2021-06-29 | 公開日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5. Nat Commun, 12, 2021
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7P03
| Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in inward-facing conformation without nucleotides | 分子名称: | Pleiotropic ABC efflux transporter of multiple drugs | 著者 | Szewczak-Harris, A, Wagner, M, Du, D, Schmitt, L, Luisi, B.F. | 登録日 | 2021-06-29 | 公開日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5. Nat Commun, 12, 2021
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7LB8
| Structure of a ferrichrome importer FhuCDB from E. coli | 分子名称: | Iron(3+)-hydroxamate import ATP-binding protein FhuC, Iron(3+)-hydroxamate import system permease protein FhuB, Iron(3+)-hydroxamate-binding protein FhuD | 著者 | Hu, W, Zheng, H. | 登録日 | 2021-01-07 | 公開日 | 2021-11-24 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. Commun Biol, 4, 2021
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7S5V
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7S61
| Human KATP channel in open conformation, focused on Kir and one SUR, position 5 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2021-09-12 | 公開日 | 2021-12-01 | 最終更新日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7S60
| Human KATP channel in open conformation, focused on Kir and one SUR, position 4 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2021-09-12 | 公開日 | 2021-12-01 | 最終更新日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5Y
| Human KATP channel in open conformation, focused on Kir and one SUR, position 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2021-09-12 | 公開日 | 2021-12-01 | 最終更新日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5Z
| Human KATP channel in open conformation, focused on Kir and one SUR, position 3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2021-09-12 | 公開日 | 2021-12-01 | 最終更新日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5X
| Human KATP channel in open conformation, focused on Kir and one SUR, position 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2021-09-12 | 公開日 | 2021-12-01 | 最終更新日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OTI
| Structure of ABCB1/P-glycoprotein in apo state | 分子名称: | Multidrug resistance protein 1A | 著者 | Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F. | 登録日 | 2021-06-10 | 公開日 | 2021-12-08 | 最終更新日 | 2022-01-05 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor. Membranes (Basel), 11, 2021
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7OTG
| Structure of ABCB1/P-glycoprotein in the presence of the CFTR potentiator ivacaftor | 分子名称: | Multidrug resistance protein 1A, N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide | 著者 | Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F. | 登録日 | 2021-06-10 | 公開日 | 2021-12-08 | 最終更新日 | 2022-01-05 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor. Membranes (Basel), 11, 2021
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7PSM
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7PSL
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7PSN
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7M33
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7BG4
| Multidrug resistance transporter BmrA mutant E504A bound with ATP, Mg, and Rhodamine 6G solved by Cryo-EM | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION, ... | 著者 | Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P. | 登録日 | 2021-01-05 | 公開日 | 2022-01-12 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
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7BCW
| Structure of MsbA in Salipro with ADP vanadate | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent lipid A-core flippase, ... | 著者 | Traore, D.A.K, Tidow, H. | 登録日 | 2020-12-21 | 公開日 | 2022-01-12 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination. Febs J., 289, 2022
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7O9W
| Encequidar-bound human P-glycoprotein in complex with UIC2-Fab | 分子名称: | Multidrug resistance protein 1, UIC2 Fab-fragment heavy chain, UIC2 Fab-fragment light chain, ... | 著者 | Nosol, K, Locher, K.P. | 登録日 | 2021-04-17 | 公開日 | 2022-01-12 | 最終更新日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations. J.Med.Chem., 65, 2022
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7SVR
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7SVD
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7SV7
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7OW8
| CryoEM structure of the ABC transporter BmrA E504A mutant in complex with ATP-Mg | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | 著者 | Gobet, A, Schoehn, G, Falson, P, Chaptal, V. | 登録日 | 2021-06-17 | 公開日 | 2022-01-19 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
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