7OTI
Structure of ABCB1/P-glycoprotein in apo state
Summary for 7OTI
| Entry DOI | 10.2210/pdb7oti/pdb |
| Related | 7OTG |
| EMDB information | 13059 13060 |
| Descriptor | Multidrug resistance protein 1A (1 entity in total) |
| Functional Keywords | abcb1, abc transporters, membrane proteins, ivacaftor, mdr1, multidrug resistance, cryo-em, membrane protein |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 141877.88 |
| Authors | Ford, R.C.,Barbieri, A.,Thonghin, N.,Shafi, T.,Prince, S.M.,Collins, R.F. (deposition date: 2021-06-10, release date: 2021-12-08, Last modification date: 2022-01-05) |
| Primary citation | Barbieri, A.,Thonghin, N.,Shafi, T.,Prince, S.M.,Collins, R.F.,Ford, R.C. Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor. Membranes (Basel), 11:-, 2021 Cited by PubMed: 34940424DOI: 10.3390/membranes11120923 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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