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6OX0
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SETD3 in Complex with an Actin Peptide with Sinefungin Replacing SAH as Cofactor
分子名称: 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ...
著者Horton, J.R, Dai, S, Cheng, X.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.755 Å)
主引用文献Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
1TTU
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Crystal Structure of CSL bound to DNA
分子名称: 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', ...
著者Kovall, R.A, Hendrickson, W.A.
登録日2004-06-23
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA
Embo J., 23, 2004
8GRQ
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BU of 8grq by Molmil
Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome
分子名称: BRCA1-associated RING domain protein 1, Breast cancer type 1 susceptibility protein, DNA (147-MER), ...
著者Ai, H.S, Zebin, T, Zhiheng, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L.
登録日2022-09-02
公開日2023-04-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
8SH2
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BU of 8sh2 by Molmil
KLHDC2 in complex with EloB and EloC
分子名称: Elongin-B, Elongin-C, Kelch domain-containing protein 2
著者Digianantonio, K.M, Bekes, M.
登録日2023-04-13
公開日2024-01-03
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
6OI1
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BU of 6oi1 by Molmil
Crystal structure of human WDR5 in complex with monomethyl L-arginine
分子名称: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, GLYCEROL, SULFATE ION, ...
著者Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2019-04-08
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
6OX3
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BU of 6ox3 by Molmil
SETD3 in Complex with an Actin Peptide with His73 Replaced with Lysine
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ...
著者Horton, J.R, Dai, S, Cheng, X.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.785 Å)
主引用文献Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
8RWZ
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BU of 8rwz by Molmil
Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL
分子名称: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Cullin-2, ...
著者Ciulli, A, Crowe, C, Nakacone, M.A.
登録日2024-02-05
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL
To Be Published
6OX1
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SETD3 in Complex with an Actin Peptide with Target Histidine Partially Methylated
分子名称: 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ...
著者Horton, J.R, Dai, S, Cheng, X.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OFZ
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BU of 6ofz by Molmil
Crystal structure of human WDR5
分子名称: WD repeat-containing protein 5
著者Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2019-04-01
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
7YFP
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BU of 7yfp by Molmil
The NuA4 histone acetyltransferase complex from S. cerevisiae
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ...
著者Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q.
登録日2022-07-08
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of the NuA4 histone acetyltransferase complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
6OX4
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BU of 6ox4 by Molmil
A SETD3 Mutant (N255A) in Complex with an Actin Peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ...
著者Horton, J.R, Dai, S, Cheng, X.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
1R39
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BU of 1r39 by Molmil
THE STRUCTURE OF P38ALPHA
分子名称: Mitogen-activated protein kinase 14, SULFATE ION
著者Patel, S.B, Cameron, P.M, Frantz-Wattley, B, O'Neill, E, Becker, J.W, Scapin, G.
登録日2003-10-01
公開日2004-01-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Lattice stabilization and enhanced diffraction in human p38 alpha crystals by protein engineering.
Biochim.Biophys.Acta, 1696, 2004
6OX5
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BU of 6ox5 by Molmil
A SETD3 Mutant (N255A) in Complex with an Actin Peptide with His73 Replaced with Lysine
分子名称: 1,2-ETHANEDIOL, Actin Peptide, Actin-histidine N-methyltransferase, ...
著者Horton, J.R, Dai, S, Cheng, X.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OI2
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BU of 6oi2 by Molmil
Crystal structure of human WDR5 in complex with symmetric dimethyl-L-arginine
分子名称: GLYCEROL, N3, N4-DIMETHYLARGININE, ...
著者Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2019-04-08
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
6OX2
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BU of 6ox2 by Molmil
SETD3in Complex with an Actin Peptide with the Target Histidine Fully Methylated
分子名称: 1,2-ETHANEDIOL, Actin Peptide, GLYCEROL, ...
著者Horton, J.R, Dai, S, Cheng, X.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.089 Å)
主引用文献Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
5EGA
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BU of 5ega by Molmil
2009 H1N1 PA endonuclease domain in complex with an N-acylhydrazone inhibitor
分子名称: 3,4,5-tris(oxidanyl)-~{N}-[(~{E})-[3,4,5-tris(oxidanyl)phenyl]methylideneamino]benzamide, MANGANESE (II) ION, Polymerase acidic protein
著者Kumar, G, White, S.W.
登録日2015-10-26
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes.
Sci Rep, 6, 2016
7VVY
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BU of 7vvy by Molmil
TRA module of NuA4
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
著者Chen, Z, Qu, K.
登録日2021-11-09
公開日2022-08-10
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022
7YFN
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BU of 7yfn by Molmil
Core module of the NuA4 complex in S. cerevisiae
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ...
著者Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q.
登録日2022-07-08
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the NuA4 histone acetyltransferase complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
4O45
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BU of 4o45 by Molmil
WDR5 in complex with influenza NS1 C-terminal tail
分子名称: Nonstructural protein 1, UNKNOWN ATOM OR ION, WD repeat-containing protein 5
著者Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2013-12-18
公開日2014-04-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
7N40
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BU of 7n40 by Molmil
Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex
分子名称: Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog
著者Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M.
登録日2021-06-02
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.
Nat Commun, 13, 2022
3WTW
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BU of 3wtw by Molmil
Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
著者Shiina, M, Hamada, K, Ogata, K.
登録日2014-04-21
公開日2014-08-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTX
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BU of 3wtx by Molmil
Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
著者Shiina, M, Hamada, K, Ogata, K.
登録日2014-04-21
公開日2014-08-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTY
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BU of 3wty by Molmil
Crystal structure of the complex comprised of ETS1(G333P), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
著者Shiina, M, Hamada, K, Ogata, K.
登録日2014-04-21
公開日2014-08-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTV
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BU of 3wtv by Molmil
Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ...
著者Shiina, M, Hamada, K, Ogata, K.
登録日2014-04-21
公開日2014-08-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
3WTT
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BU of 3wtt by Molmil
Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA
分子名称: 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ...
著者Shiina, M, Hamada, K, Ogata, K.
登録日2014-04-21
公開日2014-08-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015

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件を2024-08-07に公開中

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