6OX0
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![BU of 6ox0 by Molmil](/molmil-images/mine/6ox0) | SETD3 in Complex with an Actin Peptide with Sinefungin Replacing SAH as Cofactor | 分子名称: | 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ... | 著者 | Horton, J.R, Dai, S, Cheng, X. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | 主引用文献 | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
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1TTU
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![BU of 1ttu by Molmil](/molmil-images/mine/1ttu) | Crystal Structure of CSL bound to DNA | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', ... | 著者 | Kovall, R.A, Hendrickson, W.A. | 登録日 | 2004-06-23 | 公開日 | 2004-08-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA Embo J., 23, 2004
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8GRQ
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![BU of 8grq by Molmil](/molmil-images/mine/8grq) | Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome | 分子名称: | BRCA1-associated RING domain protein 1, Breast cancer type 1 susceptibility protein, DNA (147-MER), ... | 著者 | Ai, H.S, Zebin, T, Zhiheng, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L. | 登録日 | 2022-09-02 | 公開日 | 2023-04-12 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination. Chem, 2023
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8SH2
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![BU of 8sh2 by Molmil](/molmil-images/mine/8sh2) | KLHDC2 in complex with EloB and EloC | 分子名称: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | 著者 | Digianantonio, K.M, Bekes, M. | 登録日 | 2023-04-13 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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6OI1
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![BU of 6oi1 by Molmil](/molmil-images/mine/6oi1) | Crystal structure of human WDR5 in complex with monomethyl L-arginine | 分子名称: | (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, GLYCEROL, SULFATE ION, ... | 著者 | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | 登録日 | 2019-04-08 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59, 2020
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6OX3
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![BU of 6ox3 by Molmil](/molmil-images/mine/6ox3) | SETD3 in Complex with an Actin Peptide with His73 Replaced with Lysine | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ... | 著者 | Horton, J.R, Dai, S, Cheng, X. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.785 Å) | 主引用文献 | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
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8RWZ
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![BU of 8rwz by Molmil](/molmil-images/mine/8rwz) | Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Cullin-2, ... | 著者 | Ciulli, A, Crowe, C, Nakacone, M.A. | 登録日 | 2024-02-05 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL To Be Published
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6OX1
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![BU of 6ox1 by Molmil](/molmil-images/mine/6ox1) | SETD3 in Complex with an Actin Peptide with Target Histidine Partially Methylated | 分子名称: | 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ... | 著者 | Horton, J.R, Dai, S, Cheng, X. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
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6OFZ
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![BU of 6ofz by Molmil](/molmil-images/mine/6ofz) | Crystal structure of human WDR5 | 分子名称: | WD repeat-containing protein 5 | 著者 | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | 登録日 | 2019-04-01 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59, 2020
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7YFP
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![BU of 7yfp by Molmil](/molmil-images/mine/7yfp) | The NuA4 histone acetyltransferase complex from S. cerevisiae | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ... | 著者 | Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q. | 登録日 | 2022-07-08 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of the NuA4 histone acetyltransferase complex. Proc.Natl.Acad.Sci.USA, 119, 2022
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6OX4
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![BU of 6ox4 by Molmil](/molmil-images/mine/6ox4) | A SETD3 Mutant (N255A) in Complex with an Actin Peptide | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ... | 著者 | Horton, J.R, Dai, S, Cheng, X. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | 主引用文献 | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
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1R39
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![BU of 1r39 by Molmil](/molmil-images/mine/1r39) | THE STRUCTURE OF P38ALPHA | 分子名称: | Mitogen-activated protein kinase 14, SULFATE ION | 著者 | Patel, S.B, Cameron, P.M, Frantz-Wattley, B, O'Neill, E, Becker, J.W, Scapin, G. | 登録日 | 2003-10-01 | 公開日 | 2004-01-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Lattice stabilization and enhanced diffraction in human p38 alpha crystals by protein engineering. Biochim.Biophys.Acta, 1696, 2004
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6OX5
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![BU of 6ox5 by Molmil](/molmil-images/mine/6ox5) | A SETD3 Mutant (N255A) in Complex with an Actin Peptide with His73 Replaced with Lysine | 分子名称: | 1,2-ETHANEDIOL, Actin Peptide, Actin-histidine N-methyltransferase, ... | 著者 | Horton, J.R, Dai, S, Cheng, X. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | 主引用文献 | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
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6OI2
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![BU of 6oi2 by Molmil](/molmil-images/mine/6oi2) | Crystal structure of human WDR5 in complex with symmetric dimethyl-L-arginine | 分子名称: | GLYCEROL, N3, N4-DIMETHYLARGININE, ... | 著者 | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | 登録日 | 2019-04-08 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59, 2020
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6OX2
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![BU of 6ox2 by Molmil](/molmil-images/mine/6ox2) | SETD3in Complex with an Actin Peptide with the Target Histidine Fully Methylated | 分子名称: | 1,2-ETHANEDIOL, Actin Peptide, GLYCEROL, ... | 著者 | Horton, J.R, Dai, S, Cheng, X. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.089 Å) | 主引用文献 | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
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5EGA
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![BU of 5ega by Molmil](/molmil-images/mine/5ega) | 2009 H1N1 PA endonuclease domain in complex with an N-acylhydrazone inhibitor | 分子名称: | 3,4,5-tris(oxidanyl)-~{N}-[(~{E})-[3,4,5-tris(oxidanyl)phenyl]methylideneamino]benzamide, MANGANESE (II) ION, Polymerase acidic protein | 著者 | Kumar, G, White, S.W. | 登録日 | 2015-10-26 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes. Sci Rep, 6, 2016
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7VVY
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![BU of 7vvy by Molmil](/molmil-images/mine/7vvy) | TRA module of NuA4 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | 著者 | Chen, Z, Qu, K. | 登録日 | 2021-11-09 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the NuA4 acetyltransferase complex bound to the nucleosome. Nature, 610, 2022
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7YFN
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![BU of 7yfn by Molmil](/molmil-images/mine/7yfn) | Core module of the NuA4 complex in S. cerevisiae | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ... | 著者 | Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q. | 登録日 | 2022-07-08 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the NuA4 histone acetyltransferase complex. Proc.Natl.Acad.Sci.USA, 119, 2022
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4O45
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![BU of 4o45 by Molmil](/molmil-images/mine/4o45) | WDR5 in complex with influenza NS1 C-terminal tail | 分子名称: | Nonstructural protein 1, UNKNOWN ATOM OR ION, WD repeat-containing protein 5 | 著者 | Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-18 | 公開日 | 2014-04-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
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7N40
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![BU of 7n40 by Molmil](/molmil-images/mine/7n40) | Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex | 分子名称: | Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog | 著者 | Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. | 登録日 | 2021-06-02 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes. Nat Commun, 13, 2022
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3WTW
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![BU of 3wtw by Molmil](/molmil-images/mine/3wtw) | Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WTX
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![BU of 3wtx by Molmil](/molmil-images/mine/3wtx) | Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WTY
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![BU of 3wty by Molmil](/molmil-images/mine/3wty) | Crystal structure of the complex comprised of ETS1(G333P), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WTV
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![BU of 3wtv by Molmil](/molmil-images/mine/3wtv) | Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WTT
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![BU of 3wtt by Molmil](/molmil-images/mine/3wtt) | Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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