1E7L
| Endonuclease VII (EndoVII) N62D mutant from phage T4 | 分子名称: | RECOMBINATION ENDONUCLEASE VII, SULFATE ION, ZINC ION | 著者 | Raaijmakers, H.C.A, Vix, O, Toro, I, Suck, D. | 登録日 | 2000-08-29 | 公開日 | 2001-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Conformational Flexibility in T4 Endonuclease Vii Revealed by Crystallography: Implications for Substrate Binding and Cleavage J.Mol.Biol., 308, 2001
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1E7M
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1E7N
| The N-terminal domain of beta-B2-crystallin resembles the putative ancestral homodimer | 分子名称: | BETA-CRYSTALLIN B2 | 著者 | Clout, N.J, Basak, A, Wieligmann, K, Bateman, O.A, Jaenicke, R, Slingsby, C. | 登録日 | 2000-08-31 | 公開日 | 2000-10-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The N-Terminal Domain of Betab2-Crystallin Resembles the Putative Ancestral Homodimer. J.Mol.Biol., 304, 2000
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1E7O
| A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V44I, V58L MUTATIONS | 分子名称: | GLYCEROL, SPECTRIN ALPHA CHAIN | 著者 | Vega, M.C, Serrano, L. | 登録日 | 2000-08-31 | 公開日 | 2003-05-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | A Thermodynamic and Kinetic Analysis of the Folding Pathway of an SH3 Domain Entropically Stabilised by a Redesigned Hydrophobic Core J.Mol.Biol., 328, 2003
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1E7P
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1E7Q
| GDP 4-keto-6-deoxy-D-mannose epimerase reductase S107A | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... | 著者 | Rosano, C, Izzo, G, Bolognesi, M. | 登録日 | 2000-09-07 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
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1E7R
| GDP 4-keto-6-deoxy-D-mannose epimerase reductase Y136E | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... | 著者 | Rosano, C, Izzo, G, Bolognesi, M. | 登録日 | 2000-09-07 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
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1E7S
| GDP 4-keto-6-deoxy-D-mannose epimerase reductase K140R | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... | 著者 | Rosano, C, Zuccotti, S, Izzo, G, Bolognesi, M. | 登録日 | 2000-09-07 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
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1E7U
| Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine | 分子名称: | (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | 著者 | Walker, E.H, Perisic, O, Ried, C, Stephens, L, Williams, R.L. | 登録日 | 2000-09-08 | 公開日 | 2000-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
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1E7V
| Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine | 分子名称: | 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | 著者 | Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L. | 登録日 | 2000-09-08 | 公開日 | 2000-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol.Cell, 6, 2000
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1E7W
| One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes | 分子名称: | 1,2-ETHANEDIOL, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Gourley, D.G, Hunter, W.N. | 登録日 | 2000-09-11 | 公開日 | 2001-09-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites. Nat.Struct.Biol., 8, 2001
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1E7Y
| ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES COMPLEXED WITH SUBSTRATE AND NADPH | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, ... | 著者 | Adams, M.J, Cosgrove, M.S, Gover, S. | 登録日 | 2000-09-12 | 公開日 | 2000-12-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme Biochemistry, 39, 2000
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1E7Z
| Crystal structure of the EMAP2/RNA binding domain of the p43 protein from human aminoacyl-tRNA synthetase complex | 分子名称: | ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II, MERCURY (II) ION | 著者 | Pasqualato, S, Kerjan, P, Renault, L, Menetrey, J, Mirande, M, Cherfils, J. | 登録日 | 2000-09-13 | 公開日 | 2000-11-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of the Emapii Domain of Human Aminoacyl-tRNA Synthetase Complex Reveals Evolutionary Dimeric Mimicry Embo J., 20, 2001
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1E80
| Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133 | 分子名称: | 4-amino-N-{(1R,8R,9R,13R)-16-(4-amino-2-methylpyrimidin-5-yl)-1-benzyl-8-(cyclohexylmethyl)-9-hydroxy-13-[(1S)-1-methylpropyl]-2,6,11,14-tetraoxo-3,7,12,15-tetraazahexadec-1-yl}piperidine-1-carboxamide, ENDOTHIAPEPSIN | 著者 | Read, J.A, Cooper, J.B, Toldo, L, Rippmann, F, Raddatz, P. | 登録日 | 2000-09-15 | 公開日 | 2000-09-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Ph D Thesis, 1999
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1E81
| Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD61395 | 分子名称: | (2S)-1-{[(2R)-1-{[(2S,3S)-1-cyclohexyl-3-hydroxy-4-(2-oxopyridin-1(2H)-yl)butan-2-yl]amino}-3-(methylsulfanyl)-1-oxopropan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl 4-aminopiperidine-1-carboxylate, ENDOTHIAPEPSIN | 著者 | Read, J.A, Cooper, J.B, Toldo, L, Rippmann, F, Raddatz, P. | 登録日 | 2000-09-15 | 公開日 | 2000-10-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Thesis, 1999
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1E82
| Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601 | 分子名称: | (2S)-1-{[(2R)-1-{[(2S,3R)-1-cyclohexyl-3-hydroxy-4-(pyridin-4-yloxy)butan-2-yl]amino}-3-(methylsulfanyl)-1-oxopropan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl 4-aminopiperidine-1-carboxylate, ENDOTHIAPEPSIN | 著者 | Read, J.A, Cooper, J.B, Toldo, L, Rippmann, F, Raddatz, P. | 登録日 | 2000-09-15 | 公開日 | 2000-10-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Thesis, 1999
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1E83
| Cytochrome c' from Alcaligenes xylosoxidans - oxidized structure | 分子名称: | CYTOCHROME C', HEME C | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
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1E84
| Cytochrome c' from Alcaligenes xylosoxidans - reduced structure | 分子名称: | CYTOCHROME C', HEME C | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
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1E85
| Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with NO bound to proximal side of heme | 分子名称: | CYTOCHROME C', HEME C, NITRIC OXIDE | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase. Embo J., 19, 2000
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1E86
| Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with CO bound to distal side of heme | 分子名称: | CARBON MONOXIDE, CYTOCHROME C', HEME C | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
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1E87
| Human CD69 - trigonal form | 分子名称: | EARLY ACTIVATION ANTIGEN CD69, GLYCEROL, ZINC ION | 著者 | Tormo, J. | 登録日 | 2000-09-18 | 公開日 | 2000-09-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of the C-Type Lectin-Like Domain from the Human Hematopoietic Cell Receptor Cd69 J.Biol.Chem., 276, 2001
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1E88
| Solution structure of 6F11F22F2, a compact three-module fragment of the gelatin-binding domain of human fibronectin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FIBRONECTIN | 著者 | Pickford, A.R, Smith, S.P, Staunton, D, Boyd, J, Campbell, I.D. | 登録日 | 2000-09-18 | 公開日 | 2000-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The Hairpin Structure of the (6)F1(1)F2(2)F2 Fragment from Human Fibronectin Enhances Gelatin Binding Embo J., 20, 2001
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1E89
| ON THE MECHANISM OF CYANOGENESIS CATALYZED BY HYDROXYNITRILE LYASE FROM MANIHOT ESCULENTA. CRYSTAL STRUCTURE OF ACTIVE SITE MUTANT SER80ALA IN COMPLEX WITH ACETONE CYANOHYDRIN | 分子名称: | HYDROXYNITRILE LYASE | 著者 | Lauble, H, Miehlich, B, Foerster, S, Wajant, H, Effenberger, F. | 登録日 | 2000-09-18 | 公開日 | 2001-08-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanistic Aspects of Cyanogenesis from Active-Site Mutant Ser80Ala of Hydroxynitrile Lyase from Manihot Esculenta in Complex with Acetone Cyanohydrin Protein Sci., 10, 2001
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1E8A
| The three-dimensional structure of human S100A12 | 分子名称: | CALCIUM ION, S100A12 | 著者 | Moroz, O.V, Antson, A.A, Murshudov, G.N, Maitland, N.J, Dodson, G.G, Wilson, K.S, Skibshoj, I, Lukanidin, E.M, Bronstein, I.B. | 登録日 | 2000-09-18 | 公開日 | 2001-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Three-Dimensional Structure of Human S100A12 Acta Crystallogr.,Sect.D, 57, 2001
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1E8B
| Solution structure of 6F11F22F2, a compact three-module fragment of the gelatin-binding domain of human fibronectin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FIBRONECTIN | 著者 | Pickford, A.R, Smith, S.P, Staunton, D, Boyd, J, Campbell, I.D. | 登録日 | 2000-09-18 | 公開日 | 2000-10-15 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The Hairpin Structure of the (6)F1(1)F2(2)F2 Fragment from Human Fibronectin Enhances Gelatin Binding Embo J., 20, 2001
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