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1E82

Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601

Summary for 1E82
Entry DOI10.2210/pdb1e82/pdb
Related1E5O 1E80 1E81 1EED 1ENT 1EPL 1EPM 1EPN 1EPO 1EPP 1EPQ 1EPR 1ER8 2ER0 2ER6 2ER7 2ER9 3ER3 3ER5 4APE 4ER1 4ER2 4ER4 5ER1 5ER2
DescriptorENDOTHIAPEPSIN, (2S)-1-{[(2R)-1-{[(2S,3R)-1-cyclohexyl-3-hydroxy-4-(pyridin-4-yloxy)butan-2-yl]amino}-3-(methylsulfanyl)-1-oxopropan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl 4-aminopiperidine-1-carboxylate (3 entities in total)
Functional Keywordsacid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceENDOTHIA PARASITICA
Total number of polymer chains1
Total formula weight34469.70
Authors
Read, J.A.,Cooper, J.B.,Toldo, L.,Rippmann, F.,Raddatz, P. (deposition date: 2000-09-15, release date: 2000-10-19, Last modification date: 2023-12-13)
Primary citationRead, J.A.
Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases.
Thesis, 1999
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

217705

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