4ER1
THE ACTIVE SITE OF ASPARTIC PROTEINASES
Summary for 4ER1
Entry DOI | 10.2210/pdb4er1/pdb |
Related PRD ID | PRD_000382 |
Descriptor | ENDOTHIAPEPSIN, N-[(1R,2R,4R)-1-(cyclohexylmethyl)-2-hydroxy-6-methyl-4-{[(2R)-2-methylbutyl]carbamoyl}heptyl]-3-(1H-imidazol-3-ium-4-yl)-N~2~-[3-naphthalen-1-yl-2-(naphthalen-1-ylmethyl)propanoyl]-L-alaninamide (3 entities in total) |
Functional Keywords | acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Cryphonectria parasitica (chestnut blight fungus) |
Total number of polymer chains | 1 |
Total formula weight | 34628.97 |
Authors | Quail, J.W.,Cooper, J.B.,Szelke, M.,Blundell, T.L. (deposition date: 1990-10-14, release date: 1991-01-15, Last modification date: 2017-11-29) |
Primary citation | Pearl, L.,Blundell, T. The active site of aspartic proteinases FEBS Lett., 174:96-101, 1984 Cited by PubMed: 6381096DOI: 10.1016/0014-5793(84)81085-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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