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1E7Y

ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES COMPLEXED WITH SUBSTRATE AND NADPH

Summary for 1E7Y
Entry DOI10.2210/pdb1e7y/pdb
Related1DPG 1E77 1E7M 2DPG
DescriptorGLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, 6-O-phosphono-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
Functional Keywordsoxidoreductase, oxidoreductase (choh(d) - nad(p)), glucose metabolism
Biological sourceLEUCONOSTOC MESENTEROIDES
Total number of polymer chains1
Total formula weight55414.30
Authors
Adams, M.J.,Cosgrove, M.S.,Gover, S. (deposition date: 2000-09-12, release date: 2000-12-11, Last modification date: 2020-07-29)
Primary citationCosgrove, M.S.,Gover, S.,Naylor, C.E.,Vandeputte-Rutten, L.,Adams, M.J.,Levy, H.R.
An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme
Biochemistry, 39:15002-, 2000
Cited by
PubMed: 11106478
DOI: 10.1021/BI0014608
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.48 Å)
Structure validation

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