6BZR
 
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2RDD
 | | X-ray crystal structure of AcrB in complex with a novel transmembrane helix. | | 分子名称: | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, Acriflavine resistance protein B, UPF0092 membrane protein yajC | | 著者 | Tornroth-Horsefield, S, Gourdon, P, Horsefield, R, Neutze, R. | | 登録日 | 2007-09-22 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist.
Structure, 15, 2007
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6S7P
 | | Nucleotide bound ABCB4 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ... | | 著者 | Olsen, J.A, Alam, A, Kowal, J, Stieger, B, Locher, K.P. | | 登録日 | 2019-07-05 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human lipid exporter ABCB4 in a lipid environment.
Nat.Struct.Mol.Biol., 27, 2020
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2GIF
 | | Asymmetric structure of trimeric AcrB from Escherichia coli | | 分子名称: | Acriflavine resistance protein B, CITRATE ANION | | 著者 | Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. | | 登録日 | 2006-03-28 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism.
Science, 313, 2006
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2HRT
 | | Asymmetric structure of trimeric AcrB from Escherichia coli | | 分子名称: | Acriflavine resistance protein B, CITRATE ANION | | 著者 | Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. | | 登録日 | 2006-07-20 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism.
Science, 313, 2006
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3FPP
 | | Crystal structure of E.coli MacA | | 分子名称: | Macrolide-specific efflux protein macA | | 著者 | Yum, S, Xu, Y, Piao, S, Ha, N.-C. | | 登録日 | 2009-01-06 | | 公開日 | 2009-04-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump
J.Mol.Biol., 387, 2009
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7DQV
 | | Crystal structure of a CmABCB1 mutant | | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, MAGNESIUM ION, NITRATE ION, ... | | 著者 | Matsuoka, K, Nakatsu, T, Kato, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The crystal structure of the CmABCB1 G132V mutant, which favors the outward-facing state, reveals the mechanism of the pivotal joint between TM1 and TM3.
Protein Sci., 30, 2021
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6FV6
 | | Monomer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | 分子名称: | Aq128 | | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | 登録日 | 2018-03-01 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Monomer structure of Aq128 in the outward-facing state
To Be Published
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6FV7
 | | Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | 分子名称: | Aq128 | | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | 登録日 | 2018-03-01 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Dimer structure of Aq128 in the outward-facing state
To Be Published
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7O3N
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7O3M
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7O3L
 | | Crystal Structure of AcrB Double Mutant | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Efflux pump membrane transporter | | 著者 | Ababou, A. | | 登録日 | 2021-04-02 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.526 Å) | | 主引用文献 | Crystal Structure of AcrB Double Mutant
To Be Published
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5IUY
 | | Structural insights of the outer-membrane channel OprN | | 分子名称: | CHLORIDE ION, FORMIC ACID, Multidrug efflux outer membrane protein OprN, ... | | 著者 | Ntsogo, Y, Garnier, C, Phan, G, Monlezun, L, Benas, P, Broutin, I. | | 登録日 | 2016-03-18 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Xenon for tunnelling analysis of the efflux pump component OprN.
PLoS ONE, 12, 2017
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4MT4
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3D9B
 | | Symmetric structure of E. coli AcrB | | 分子名称: | Acriflavine resistance protein B, NICKEL (II) ION | | 著者 | Veesler, D, Blangy, S, Cambillau, C, Sciara, G. | | 登録日 | 2008-05-27 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | There is a baby in the bath water: AcrB contamination is a major problem in membrane-protein crystallization.
Acta Crystallogr.,Sect.F, 64, 2008
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2XMN
 | | High resolution snapshots of defined TolC open states present an iris- like movement of periplasmic entrance helices | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Outer membrane protein TolC | | 著者 | Pei, X.Y, Koronakis, E, Hughes, C, Koronakis, V. | | 登録日 | 2010-07-28 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structures of sequential open states in a symmetrical opening transition of the TolC exit duct.
Proc. Natl. Acad. Sci. U.S.A., 108, 2011
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2VDE
 | | Crystal Structure of the Open State of TolC Outer Membrane Component of Mutlidrug Efflux Pumps | | 分子名称: | CHLORIDE ION, OUTER MEMBRANE PROTEIN TOLC | | 著者 | Bavro, V.N, Pietras, Z, Furnham, N, Perez-Cano, L, Fernandez-Recio, J, Pei, X.Y, Truer, R, Misra, R, Luisi, B. | | 登録日 | 2007-10-04 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Assembly and Channel Opening in a Bacterial Drug Efflux Machine.
Mol.Cell, 30, 2008
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2VDD
 | | Crystal Structure of the Open State of TolC Outer Membrane Component of Mutlidrug Efflux Pumps | | 分子名称: | CHLORIDE ION, OUTER MEMBRANE PROTEIN TOLC, POTASSIUM ION | | 著者 | Bavro, V.N, Pietras, Z, Furnham, N, Perez-Cano, L, Fernandez-Recio, J, Pei, X.Y, Truer, R, Misra, R, Luisi, B. | | 登録日 | 2007-10-04 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Assembly and Channel Opening in a Bacterial Drug Efflux Machine.
Mol.Cell, 30, 2008
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5WVM
 | | Crystal structure of baeS cocrystallized with 2 mM indole | | 分子名称: | Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION | | 著者 | Wang, W, Zhang, Y, Rang, T, Xu, D. | | 登録日 | 2016-12-26 | | 公開日 | 2018-01-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14
Proteins, 85, 2017
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5WVN
 | | Crystal structure of MBS-BaeS fusion protein | | 分子名称: | Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION | | 著者 | Wang, W, Zhang, Y, Ran, T, Xu, D. | | 登録日 | 2016-12-26 | | 公開日 | 2018-01-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14
Proteins, 85, 2017
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4MT0
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7K98
 | | Preaminoacylation complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine (F-AMS) | | 分子名称: | 5'-O-(L-phenylalanylsulfamoyl)adenosine, CHLORIDE ION, GLYCEROL, ... | | 著者 | Michalska, K, Chang, C, Jedrzejczak, R, Wower, J, Baragana, B, Forte, B, Gilbert, I.H, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-09-28 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
Nucleic Acids Res., 49, 2021
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7KA0
 | | Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and phenylalanine | | 分子名称: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Chang, C, Michalska, K, Jedrzejczak, R, Wower, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-09-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
Nucleic Acids Res., 49, 2021
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7K9M
 | | Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine | | 分子名称: | 5'-O-(L-phenylalanylsulfamoyl)adenosine, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | 著者 | Michalska, K, Chang, C, Jedrzejczak, R, Wower, J, Baragana, B, Forte, B, Gilbert, I.H, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-09-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
Nucleic Acids Res., 49, 2021
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7KAB
 | | M. tuberculosis PheRS complex with cognate precursor tRNA and phenylalanine | | 分子名称: | GLYCEROL, MAGNESIUM ION, PHENYLALANINE, ... | | 著者 | Chang, C, Michalska, K, Jedrzejczak, R, Wower, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-09-30 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
Nucleic Acids Res., 49, 2021
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