7K9M

Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine

Summary for 7K9M

• Entry DOI: 10.2210/pdb7k9m/pdb
• Related: 7K98 7KA0
• Descriptor: Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, tRNA(Phe), ... (9 entities in total)
• Functional Keywords: aminoacylation, phenylalanyl trna synthetase, adenylate analog, ligase-rna complex, structural genomics, center for structural genomics of infectious diseases, csgid, ligase/rna
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 3
• Total formula weight: 152768.88

Authors

Michalska, K.,Chang, C.,Jedrzejczak, R.,Wower, J.,Baragana, B.,Forte, B.,Gilbert, I.H.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-09-29, release date: 2021-05-12, Last modification date: 2023-10-18)

• Primary citation: Michalska, K.,Jedrzejczak, R.,Wower, J.,Chang, C.,Baragana, B.,Gilbert, I.H.,Forte, B.,Joachimiak, A.; Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.; Nucleic Acids Res., 49:5351-5368, 2021; PubMed: 33885823; DOI: 10.1093/nar/gkab272

Experimental method

X-RAY DIFFRACTION (2.5 Å)