7K9M
Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phenylalanine--tRNA ligase alpha subunit | polymer | 341 | 37415.3 | 1 | UniProt (P9WFU3) Pfam (PF02912) Pfam (PF01409) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Phenylalanyl-tRNA synthetase alpha subunit,PheRS |
| 2 | B (B) | Phenylalanine--tRNA ligase beta subunit | polymer | 835 | 88867.2 | 1 | UniProt (P9WFU1) Pfam (PF01588) Pfam (PF03483) Pfam (PF03484) Pfam (PF17759) Pfam (PF03147) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Phenylalanyl-tRNA synthetase beta subunit,PheRS |
| 3 | C (C) | tRNA(Phe) | polymer | 77 | 24842.8 | 1 | GenBank (1251771558) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 4 | D (A) | 5'-O-(L-phenylalanylsulfamoyl)adenosine | non-polymer | 493.5 | 1 | Chemie (W5Y) | |||
| 5 | E, F, K (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 6 | G, H, I, J, N... (A, B) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 7 | L (B) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 8 | M (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 9 | Q, R, S (A, B, C) | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
B: 1 - 831 (UniProt: P9WFU1)
| PDB | External Database | Details |
|---|---|---|
| Gln -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 151125.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1643.6 | |
| All* | Total formula weight | 152768.9 |
