7KA0

Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and phenylalanine

Summary for 7KA0

• Entry DOI: 10.2210/pdb7ka0/pdb
• Related: 7K98 7K9M
• Descriptor: Phenylalanine--tRNA ligase alpha subunit, POTASSIUM ION, Phenylalanine--tRNA ligase beta subunit, ... (11 entities in total)
• Functional Keywords: aminoacylation, phenylalanyl trna synthetase, structural genomics, ligase-trna complex, center for structural genomics of infectious diseases, csgid, ligase-rna complex, ligase/rna
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 6
• Total formula weight: 305336.13

Authors

Chang, C.,Michalska, K.,Jedrzejczak, R.,Wower, J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-09-29, release date: 2021-05-12, Last modification date: 2023-10-18)

• Primary citation: Michalska, K.,Jedrzejczak, R.,Wower, J.,Chang, C.,Baragana, B.,Gilbert, I.H.,Forte, B.,Joachimiak, A.; Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.; Nucleic Acids Res., 49:5351-5368, 2021; PubMed: 33885823; DOI: 10.1093/nar/gkab272

Experimental method

X-RAY DIFFRACTION (2.4 Å)