7K98

Preaminoacylation complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine (F-AMS)

Summary for 7K98

Entry DOI	10.2210/pdb7k98/pdb
Descriptor	Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, tRNA(Phe), ... (8 entities in total)
Functional Keywords	aminoacylation, phenylalanyl trna synthetase, adenylate analog, structural genomics, center for structural genomics of infectious diseases, csgid, ligase-rna complex, ligase/rna
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More
Total number of polymer chains	6
Total formula weight	305778.73
Authors	Michalska, K.,Chang, C.,Jedrzejczak, R.,Wower, J.,Baragana, B.,Forte, B.,Gilbert, I.H.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-09-28, release date: 2021-05-12, Last modification date: 2023-10-18)
Primary citation	Michalska, K.,Jedrzejczak, R.,Wower, J.,Chang, C.,Baragana, B.,Gilbert, I.H.,Forte, B.,Joachimiak, A. Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation. Nucleic Acids Res., 49:5351-5368, 2021 Cited by PubMed: 33885823 DOI: 10.1093/nar/gkab272 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation