2RDD

X-ray crystal structure of AcrB in complex with a novel transmembrane helix.

Summary for 2RDD

Entry DOI	10.2210/pdb2rdd/pdb
Related	1IWG 1OY8 2DHH 2GIF 2HQC 2J8S
Descriptor	Acriflavine resistance protein B, UPF0092 membrane protein yajC, (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID (3 entities in total)
Functional Keywords	drug resistance, multidrug efflux, transporter, antiporter, membrane protein, novel transmembrane helix, acrb, yajc, inner membrane, membrane protein-transport protein complex, membrane protein/transport protein
Biological source	Escherichia coli More
Cellular location	Cell inner membrane; Multi-pass membrane protein: P31224 Cell inner membrane; Single-pass membrane protein: P0ADZ7
Total number of polymer chains	2
Total formula weight	118811.50
Authors	Tornroth-Horsefield, S.,Gourdon, P.,Horsefield, R.,Neutze, R. (deposition date: 2007-09-22, release date: 2007-12-11, Last modification date: 2023-08-30)
Primary citation	Tornroth-Horsefield, S.,Gourdon, P.,Horsefield, R.,Brive, L.,Yamamoto, N.,Mori, H.,Snijder, A.,Neutze, R. Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist. Structure, 15:1663-1673, 2007 Cited by PubMed: 18073115 DOI: 10.1016/j.str.2007.09.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation