2J8S
Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors
Summary for 2J8S
Entry DOI | 10.2210/pdb2j8s/pdb |
Related | 1IWG 1OY6 1OY8 1OY9 1OYD 1OYE 1T9T 1T9U 1T9V 1T9W 1T9X 1T9Y 2GIF 2HRT |
Descriptor | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ... (5 entities in total) |
Functional Keywords | membrane protein-complex, designed ankyrin repeat protein, multidrug resistance protein, co-crystallization, antibiotic resistance, inner membrane, protein complex, membrane protein, rnd, membrane, inhibitor, transport, transmembrane, drug-efflux pump, transport protein, antibiotic resistance-inhibitor complex |
Biological source | ESCHERICHIA COLI More |
Total number of polymer chains | 5 |
Total formula weight | 385733.97 |
Authors | Sennhauser, G.,Amstutz, P.,Briand, C.,Storchenegger, O.,Gruetter, M.G. (deposition date: 2006-10-27, release date: 2007-01-23, Last modification date: 2023-12-13) |
Primary citation | Sennhauser, G.,Amstutz, P.,Briand, C.,Storchenegger, O.,Grutter, M.G. Drug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors. Plos Biol., 5:E7-, 2007 Cited by PubMed: 17194213DOI: 10.1371/JOURNAL.PBIO.0050007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
Download full validation report