2J8S

Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	ACRIFLAVINE RESISTANCE PROTEIN B	polymer	1055	114494.0	3	UniProt (P31224) Pfam (PF00873)	ESCHERICHIA COLI	ACRB
2	D, E (D, E)	DARPIN	polymer	169	18317.6	2		SYNTHETIC CONSTRUCT
3	F, G, H, J, K... (A, B, C)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	10	Chemie (LMT)
4	I (A)	DODECYL-ALPHA-D-MALTOSIDE	non-polymer		510.6	1	Chemie (LMU) PubChem (16220143) PubChem (24802120) PubChem (25021193) PubChem (44119948) PubChem (114880) PubChem (46936627) PubChem (53393702) PubChem (56845466) PubChem (58112562) PubChem (58253045) PubChem (60087035) PubChem (68322761) PubChem (68338004) PubChem (68441652) PubChem (445456) PubChem (70796428) PubChem (70813879) PubChem (70839937) PubChem (75487624) PubChem (59615220) PubChem (3481630) PubChem (2802066) PubChem (89796216) PubChem (91094859) PubChem (90817611) PubChem (91608950) PubChem (95566087) PubChem (102565427) PubChem (95566088) PubChem (95566089) PubChem (95566090) PubChem (96327540) PubChem (97038234) PubChem (97038235) PubChem (97294875) PubChem (98046621) PubChem (98046622) PubChem (98046623) PubChem (100976848) PubChem (101111379) PubChem (101111381) PubChem (102219025) PubChem (117716045) PubChem (117753833) PubChem (118443377) PubChem (9849225) PubChem (123281924) PubChem (10413991) PubChem (124184997) PubChem (124196217) PubChem (124196220) PubChem (140505128) PubChem (153835411) PubChem (155885597) PubChem (126735853) PubChem (126735860) PubChem (169619620) PubChem (173767704) PubChem (173885518) PubChem (129720403) PubChem (134694723) PubChem (140479759) PubChem (140841257) PubChem (154810097) PubChem (159812235) PubChem (163184859)
5	Q, R, S, T, U (A, B, C, D, E)	water	water		18.0	350	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 1049 (UniProt: P31224)
A, B, C: 1050 - 1055 (PDB: 2J8S)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	380117.2
Non-Polymers*	Number of molecules	11
	Total formula weight	5616.8
All*	Total formula weight	385734.0

*Water molecules are not included.