PDB: 1358 件ウェブページステータス検索Chemie searchBIRD

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4V5J	Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights into catalysis of peptide release 分子名称: 16S Ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Jin, H, Kelley, A.C, Loakes, D, Ramakrishnan, V. 登録日 2010-03-24 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release. Proc. Natl. Acad. Sci. U.S.A., 107, 2010
4V8H	Crystal structure of HPF bound to the 70S ribosome. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Blaha, G.M, Steitz, T.A. 登録日 2011-12-11 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis. Science, 336, 2012
6ENU	Polyproline-stalled ribosome in the presence of elongation-factor P (EF-P) 分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Huter, P, Arenz, S, Wilson, D.N. 登録日 2017-10-06 公開日 2017-11-22 最終更新日 2018-01-31 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. Mol. Cell, 68, 2017
6X7K	Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Molodtsov, V, Ebright, R.H, Wang, C, Su, M. 登録日 2020-05-30 公開日 2020-09-02 最終更新日 2020-09-23 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of transcription-translation coupling. Science, 369, 2020
8V9K	Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Rv2629 (Balon) (Structure 5) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... 著者 Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. 登録日 2023-12-08 公開日 2024-02-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
8V9J	Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) (Structure 4) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S14, ... 著者 Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. 登録日 2023-12-08 公開日 2024-02-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
4V7Z	Structure of the Thermus thermophilus 70S ribosome complexed with telithromycin. 分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. 登録日 2010-08-18 公開日 2014-07-09 最終更新日 2021-01-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
8UU8	Cryo-EM structure of the Listeria innocua 70S ribosome (head-swiveled) in complex with HflXr and pe/E-tRNA (structure II-C) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... 著者 Seely, S.M, Basu, R.S, Gagnon, M.G. 登録日 2023-10-31 公開日 2024-02-28 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanistic insights into the alternative ribosome recycling by HflXr. Nucleic Acids Res., 52, 2024
7LS2	80S ribosome from mouse bound to eEF2 (Class I) 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T. 登録日 2021-02-17 公開日 2021-11-03 最終更新日 2021-12-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance. Nat Commun, 12, 2021
8UU9	Cryo-EM structure of the ratcheted Listeria innocua 70S ribosome (head-swiveled) in complex with HflXr and pe/E-tRNA (structure II-D) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... 著者 Seely, S.M, Basu, R.S, Gagnon, M.G. 登録日 2023-10-31 公開日 2024-02-28 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanistic insights into the alternative ribosome recycling by HflXr. Nucleic Acids Res., 52, 2024
5J8A	Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... 著者 Cocozaki, A, Ferguson, A. 登録日 2016-04-07 公開日 2016-07-06 最終更新日 2016-08-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
5MDZ	Structure of the 70S ribosome (empty A site) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. 登録日 2016-11-13 公開日 2016-12-14 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Translational termination without a stop codon. Science, 354, 2016
5MGP	Structural basis for ArfA-RF2 mediated translation termination on stop-codon lacking mRNAs 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Huter, P, Mueller, C, Beckert, B, Arenz, S, Berninghausen, O, Beckmann, R, Wilson, N.D. 登録日 2016-11-21 公開日 2016-12-14 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for ArfA-RF2-mediated translation termination on mRNAs lacking stop codons. Nature, 541, 2017
5J4D	E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon 分子名称: 16S ribosomal RNA, 25S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2016-03-31 公開日 2016-05-18 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis for Translation Termination on a Pseudouridylated Stop Codon. J.Mol.Biol., 428, 2016
6P5K	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
6ZUO	Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage) 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Plassart, L, Shayan, R, Plisson-Chastang, C. 登録日 2020-07-23 公開日 2021-05-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
4WQ1	Complex of 70S ribosome with tRNA-Tyr and mRNA with C-A mismatch in the first position in the A-site. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2014-10-21 公開日 2015-06-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
7P7U	E. faecalis 70S ribosome with P-tRNA, state IV 分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... 著者 Crowe-McAuliffe, C, Wilson, D.N. 登録日 2021-07-20 公開日 2022-02-23 最終更新日 2022-04-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
1XNR	Crystal Structure of an Inosine-Cytosine Wobble Base Pair in the Context of the Decoding Center 分子名称: 16S Ribosomal RNA, 16S Ribosomal protein S10, 16S Ribosomal protein S11, ... 著者 Murphy, F.V, Ramakrishnan, V. 登録日 2004-10-05 公開日 2004-12-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of a purine-purine wobble base pair in the decoding center of the ribosome. Nat.Struct.Mol.Biol., 11, 2004
4WWW	Crystal structure of the E. coli ribosome bound to CEM-101 分子名称: (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ... 著者 Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S. 登録日 2014-11-12 公開日 2014-12-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob. Agents Chemother., 54, 2010
4U4N	Crystal structure of Edeine bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4WZD	Complex of 70S ribosome with cognate tRNA-Tyr in the P-site 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2014-11-19 公開日 2015-06-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
6YBS	Structure of a human 48S translational initiation complex - head 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... 著者 Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. 登録日 2020-03-17 公開日 2020-09-16 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of a human 48Stranslational initiation complex. Science, 369, 2020
5DGV	Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog 分子名称: 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-28 公開日 2016-12-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
4V7U	Crystal structure of the E. coli ribosome bound to erythromycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. 登録日 2010-08-15 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010

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