PDB: 1252 件ウェブページステータス検索Chemie searchBIRD

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6N85	Resistance to inhibitors of cholinesterase 8A (Ric8A) protein in complex with MBP-tagged transducin-alpha residues 327-350 分子名称: Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2, Synembryn-A, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Srivastava, D, Gakhar, L, Artemyev, N.O. 登録日 2018-11-28 公開日 2019-07-10 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor. Nat Commun, 10, 2019
6NDJ	Crystal structure of human NLRP6 PYD domain with MBP fusion 分子名称: Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera 著者 Shen, C, Fu, T.M, Wu, H. 登録日 2018-12-13 公開日 2019-01-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Molecular mechanism for NLRP6 inflammasome assembly and activation. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
2E3A	Crystal structure of the NO-bound form of Arthromyces ramosus peroxidase at 1.3 Angstroms resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRIC OXIDE, ... 著者 Fukuyama, K, Okada, T. 登録日 2006-11-22 公開日 2007-03-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structures of cyanide, nitric oxide and hydroxylamine complexes of Arthromyces ramosusperoxidase at 100 K refined to 1.3 A resolution: coordination geometries of the ligands to the haem iron ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2CG8	The bifunctional dihydroneopterin aldolase 6-hydroxymethyl-7,8- dihydropterin synthase from Streptococcus pneumoniae 分子名称: DIHYDRONEOPTERIN ALDOLASE 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN SYNTHASE 著者 Garcon, A, Levy, C, Derrick, J.P. 登録日 2006-02-28 公開日 2006-06-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of the Bifunctional Dihydroneopterin Aldolase/6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase from Streptococcus Pneumoniae. J.Mol.Biol., 360, 2006
6NF1	Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity 分子名称: (2S)-3-[(3S)-1-(ethylsulfonyl)piperidin-3-yl]-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}propan-1-ol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proto-oncogene vav, ... 著者 Knapp, M.S, Elling, R.A, Ornelas, E. 登録日 2018-12-18 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity To Be Published
6NEW	Apo structure of the activated truncation of Vav1 分子名称: Proto-oncogene vav, ZINC ION 著者 Knapp, M.S, Elling, R.A, Ornelas, E. 登録日 2018-12-18 公開日 2019-12-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity To Be Published
7RJ5	The structure of BAM in complex with EspP at 7 Angstrom resolution 分子名称: Maltodextrin-binding protein,Autotransporter outer membrane beta-barrel domain-containing protein chimera, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... 著者 Wu, R.R, Noinaj, N. 登録日 2021-07-20 公開日 2021-12-22 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM. Nat Commun, 12, 2021
2E39	Crystal structure of the CN-bound form of Arthromyces ramosus peroxidase at 1.3 Angstroms resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANIDE ION, ... 著者 Fukuyama, K, Okada, T. 登録日 2006-11-22 公開日 2007-03-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structures of cyanide, nitric oxide and hydroxylamine complexes of Arthromyces ramosusperoxidase at 100 K refined to 1.3 A resolution: coordination geometries of the ligands to the haem iron ACTA CRYSTALLOGR.,SECT.D, 63, 2007
7RLU	Structure of ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP 分子名称: 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A. 登録日 2021-07-26 公開日 2022-01-12 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of putative tumor suppressor ALDH1L1. Commun Biol, 5, 2022
7RLT	Structure of ligand-free ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) 分子名称: 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase 著者 Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A. 登録日 2021-07-26 公開日 2022-01-12 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of putative tumor suppressor ALDH1L1. Commun Biol, 5, 2022
6N84	MBP-fusion protein of transducin-alpha residues 327-350 分子名称: Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Srivastava, D, Gakhar, L, Artemyev, N.O. 登録日 2018-11-28 公開日 2019-07-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor. Nat Commun, 10, 2019
2E3B	Crystal structure of the HA-bound form of Arthromyces ramosus peroxidase at 1.3 Angstroms resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HYDROXYAMINE, ... 著者 Fukuyama, K, Okada, T. 登録日 2006-11-22 公開日 2007-03-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structures of cyanide, nitric oxide and hydroxylamine complexes of Arthromyces ramosusperoxidase at 100 K refined to 1.3 A resolution: coordination geometries of the ligands to the haem iron ACTA CRYSTALLOGR.,SECT.D, 63, 2007
6NFA	Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity 分子名称: (2S)-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}-3-(pyridin-3-yl)propan-1-ol, Proto-oncogene vav, ZINC ION 著者 Knapp, M.S, Elling, R.A, Ornelas, E. 登録日 2018-12-19 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity To Be Published
2D2R	Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase 分子名称: Undecaprenyl Pyrophosphate Synthase 著者 Kuo, C.J, Guo, R.T, Chen, C.L, Ko, T.P, Cheng, Y.S, Cheng, Y.L, Liang, P.H, Wang, A.H.-J. 登録日 2005-09-16 公開日 2006-09-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases. J.Biomed.Biotechnol., 2008, 2008
2D21	NMR Structure of stereo-array isotope labelled (SAIL) maltodextrin-binding protein (MBP) 分子名称: Maltose-binding periplasmic protein 著者 Kainosho, M, Torizawa, T, Iwashita, Y, Terauchi, T, Ono, A.M, Guntert, P. 登録日 2005-09-02 公開日 2006-03-07 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Optimal isotope labelling for NMR protein structure determinations. Nature, 440, 2006
2DY0	Crystal structure of project JW0458 from Escherichia coli 分子名称: Adenine phosphoribosyltransferase, MAGNESIUM ION 著者 Shimizu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-09-04 公開日 2007-03-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure of JW0458 from Escherichia coli To be Published
6EQZ	A MamC-MIC insertion in MBP scaffold at position K170 分子名称: Maltose-binding periplasmic protein,Tightly bound bacterial magnetic particle protein,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Nudelman, H, Zarivach, R. 登録日 2017-10-16 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.293 Å) 主引用文献 The importance of the helical structure of a MamC-derived magnetite-interacting peptide for its function in magnetite formation. Acta Crystallogr D Struct Biol, 74, 2018
6USM	Structure of nuclease domain of human parvovirus B19 non-structural protein 1 in complex with zinc 分子名称: Maltodextrin-binding protein, Non-structural protein NS1, ZINC ION, ... 著者 Tewary, S.K. 登録日 2019-10-28 公開日 2020-12-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.37 Å) 主引用文献 B19 Parvovirus Non-structural protein 1 in complex with zinc To Be Published
6EG3	Crystal structure of human BRM in complex with compound 15 分子名称: 3-[(4-{[(2-chloropyridin-4-yl)carbamoyl]amino}pyridin-2-yl)ethynyl]benzoic acid, ETHANOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2 著者 Zhu, X, Kulathila, R, Hu, T, Xie, X. 登録日 2018-08-17 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. J. Med. Chem., 61, 2018
6V3E	Cryo-EM structure of the Acinetobacter baumannii Ribosome: 30S subunit 分子名称: 16s Ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Morgan, C.E, Yu, E.W. 登録日 2019-11-25 公開日 2020-02-05 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development. Mbio, 11, 2020
6EG2	Crystal structure of human BRM in complex with compound 16 分子名称: ISOPROPYL ALCOHOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2, N-(5-amino-2-chloropyridin-4-yl)-N'-(4-bromo-3-{[3-(hydroxymethyl)phenyl]ethynyl}-1,2-thiazol-5-yl)urea 著者 Zhu, X, Kulathila, R, Hu, T, Xie, X. 登録日 2018-08-17 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. J. Med. Chem., 61, 2018
6V2E	Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant 分子名称: ADM, AMINO GROUP, FORMIC ACID, ... 著者 Booe, J.M, Pioszak, A.A. 登録日 2019-11-22 公開日 2020-08-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors. Acs Pharmacol Transl Sci, 3, 2020
6V39	Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S with P-site tRNA 分子名称: 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ... 著者 Morgan, C.E, Yu, E.W. 登録日 2019-11-25 公開日 2020-02-05 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development. Mbio, 11, 2020
6FCL	Crystal Structure of Human APRT wild type in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase 著者 Nioche, P, Huyet, J, Ozeir, M. 登録日 2017-12-20 公開日 2018-08-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase. Cell Chem Biol, 25, 2018
6FD6	Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 30 days post crystallization (with AMP and PPi products fully generated) 分子名称: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, MAGNESIUM ION, ... 著者 Nioche, P, Huyet, J, Ozeir, M. 登録日 2017-12-21 公開日 2018-08-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase. Cell Chem Biol, 25, 2018

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