PDB: 96 件ウェブページステータス検索Chemie searchBIRD

---

1FFY	INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN 分子名称: ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, ... 著者 Silvian, L.F, Wang, J, Steitz, T.A. 登録日 2000-07-26 公開日 2000-08-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin. Science, 285, 1999
1GAX	CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE 分子名称: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, TRNA(VAL), VALYL-TRNA SYNTHETASE, ... 著者 Fukai, S, Nureki, O, Sekine, S, Shimada, A, Tao, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2000-06-23 公開日 2000-12-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase. Cell(Cambridge,Mass.), 103, 2000
4CQN	Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue 分子名称: ESCHERICHIA COLI TRNA-LEU UAA ISOACCEPTOR, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... 著者 Palencia, A, Cusack, S, Cvetesic, N, Haslaz, I, Gruic-Sovulj, I. 登録日 2014-02-20 公開日 2014-07-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Physiological Target for Leurs Translational Quality Control is Norvaline Embo J., 33, 2014
4AS1	Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation 分子名称: LEUCINE--TRNA LIGASE, MAGNESIUM ION, TRNA-LEU5 (UAA ISOACEPTOR) 著者 Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. 登録日 2012-04-27 公開日 2012-06-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
4ARI	Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation 分子名称: GLYCEROL, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... 著者 Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. 登録日 2012-04-24 公開日 2012-06-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
1H3N	Leucyl-tRNA synthetase from Thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate 分子名称: LEUCINE, LEUCYL-TRNA SYNTHETASE, SULFATE ION, ... 著者 Cusack, S, Yaremchuk, A, Tukalo, M. 登録日 2002-09-11 公開日 2002-09-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The 2A Structure of Leucyl-tRNA Synthetase and its Complex with a Leucyl-Adenylate Analogue Embo J., 19, 2000
5ON2	Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation 分子名称: 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... 著者 Palencia, A, Cusack, S. 登録日 2017-08-02 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
5OMW	Mutant T252A of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation 分子名称: 5'-O-(L-leucylsulfamoyl)adenosine, L-leucyl-tRNA, Leucine--tRNA ligase, ... 著者 Palencia, A, Cusack, S. 登録日 2017-08-02 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
5ONH	Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation 分子名称: 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, L-leucyl-tRNA(Leu), ... 著者 Palencia, A, Cusack, S. 登録日 2017-08-03 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
5ON3	Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation 分子名称: (2~{S})-~{N}-[(2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl]-2-azanyl-4-methyl-pentanamide, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... 著者 Palencia, A, Cusack, S. 登録日 2017-08-02 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
2BTE	Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation and a post- transfer editing substrate analogue 分子名称: 2'-AMINO-2'-DEOXYADENOSINE, AMINOACYL-TRNA SYNTHETASE, LEUCINE, ... 著者 Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S. 登録日 2005-05-31 公開日 2005-09-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer- Editing Conformation. Nat.Struct.Mol.Biol., 12, 2005
2BYT	Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation 分子名称: LEUCINE, LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, ... 著者 Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S. 登録日 2005-08-04 公開日 2005-09-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer-Editing Conformation. Nat.Struct.Mol.Biol., 12, 2005
1QU3	INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN 分子名称: ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MUPIROCIN, ... 著者 Silvian, L.F, Wang, J, Steitz, T.A. 登録日 1999-07-06 公開日 1999-08-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin. Science, 285, 1999
6KIE	Crystal structure of human leucyl-tRNA synthetase, Leu-AMS-bound form 分子名称: 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE, Leucine--tRNA ligase, ... 著者 Kim, S, Son, J, Kim, S, Hwang, K.Y. 登録日 2019-07-18 公開日 2021-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
1OBC	LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A POST-TRANSFER EDITING SUBSTRATE ANALOGUE 分子名称: 2'-AMINO-2'-DEOXYADENOSINE, LEUCINE, LEUCYL-TRNA SYNTHETASE, ... 著者 Cusack, S, Yaremchuk, A, Tukalo, M. 登録日 2003-01-30 公開日 2003-05-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase Mol.Cell, 11, 2003
1QU2	INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN 分子名称: ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, ... 著者 Silvian, L.F, Wang, J, Steitz, T.A. 登録日 1999-07-06 公開日 1999-08-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin. Science, 285, 1999
6KID	Crystal structure of human leucyl-tRNA synthetase, ATP-bound form 分子名称: ADENOSINE-5'-TRIPHOSPHATE, LEUCINE, Leucine--tRNA ligase, ... 著者 Kim, S, Son, J, Kim, S, Hwang, K.Y. 登録日 2019-07-18 公開日 2021-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
1OBH	LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A PRE-TRANSFER EDITING SUBSTRATE ANALOGUE IN BOTH SYNTHETIC ACTIVE SITE AND EDITING SITE 分子名称: LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, NORVALINE, ... 著者 Cusack, S, Yaremchuk, A, Tukalo, M. 登録日 2003-01-31 公開日 2003-05-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase Mol.Cell, 11, 2003
6KQY	Crystal structure of human leucyl-tRNA synthetase, Leucine-bound form 分子名称: LEUCINE, Leucine--tRNA ligase, cytoplasmic, ... 著者 Kim, S, Son, J, Kim, S, Hwang, K.Y. 登録日 2019-08-20 公開日 2021-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
6KR7	Crystal structure of methylated human leucyl-tRNA synthetase, Leu-AMS-bound form 分子名称: 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE, Leucine--tRNA ligase, ... 著者 Kim, S, Son, J, Kim, S, Hwang, K.Y. 登録日 2019-08-21 公開日 2021-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
1IYW	Preliminary Structure of Thermus thermophilus Ligand-Free Valyl-tRNA Synthetase 分子名称: Valyl-tRNA Synthetase 著者 Fukai, S, Nureki, O, Sekine, S, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-09-10 公開日 2003-06-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase RNA, 9, 2003
1JZQ	Isoleucyl-tRNA synthetase Complexed with Isoleucyl-adenylate analogue 分子名称: Isoleucyl-tRNA synthetase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ZINC ION 著者 Nakama, T, Nureki, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2001-09-17 公開日 2001-12-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase. J.Biol.Chem., 276, 2001
1JZS	Isoleucyl-tRNA synthetase Complexed with mupirocin 分子名称: Isoleucyl-tRNA synthetase, MUPIROCIN, ZINC ION 著者 Nakama, T, Nureki, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2001-09-17 公開日 2001-12-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase. J.Biol.Chem., 276, 2001
1IVS	CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE 分子名称: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, Valyl-tRNA synthetase, tRNA (Val) 著者 Fukai, S, Nureki, O, Sekine, S.-I, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-03-29 公開日 2003-02-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase RNA, 9, 2003
1ILE	ISOLEUCYL-TRNA SYNTHETASE 分子名称: ISOLEUCYL-TRNA SYNTHETASE, ZINC ION 著者 Nureki, O, Vassylyev, D.G, Tateno, M, Shimada, A, Nakama, T, Fukai, S, Konno, M, Schimmel, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 1998-02-24 公開日 1999-04-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Enzyme structure with two catalytic sites for double-sieve selection of substrate. Science, 280, 1998

<1234>