6KIE

Crystal structure of human leucyl-tRNA synthetase, Leu-AMS-bound form

Summary for 6KIE

• Entry DOI: 10.2210/pdb6kie/pdb
• Descriptor: Leucine--tRNA ligase, cytoplasmic, PHOSPHATE ION, 5'-O-(L-leucylsulfamoyl)adenosine, ... (5 entities in total)
• Functional Keywords: leucyl-trna synthetase, leu-ams-bound form, ligase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 123878.88

Authors

Kim, S.,Son, J.,Kim, S.,Hwang, K.Y. (deposition date: 2019-07-18, release date: 2021-01-27, Last modification date: 2023-11-22)

• Primary citation: Kim, S.,Yoon, I.,Son, J.,Park, J.,Kim, K.,Lee, J.H.,Park, S.Y.,Kang, B.S.,Han, J.M.,Hwang, K.Y.,Kim, S.; Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation.; Cell Rep, 35:109031-109031, 2021; PubMed: 33910001; DOI: 10.1016/j.celrep.2021.109031

Experimental method

X-RAY DIFFRACTION (3.15 Å)