6KIE
Crystal structure of human leucyl-tRNA synthetase, Leu-AMS-bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leucine--tRNA ligase, cytoplasmic | polymer | 1073 | 123003.3 | 1 | UniProt (Q9P2J5) Pfam (PF00133) Pfam (PF08264) Pfam (PF24810) | Homo sapiens (Human) | Leucyl-tRNA synthetase,LeuRS |
| 2 | B, C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | E (A) | 5'-O-(L-leucylsulfamoyl)adenosine | non-polymer | 459.5 | 1 | Chemie (LSS) | |||
| 4 | F (A) | LEUCINE | non-polymer | 131.2 | 1 | Chemie (LEU) | |||
| 5 | G (A) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 1 - 1061 (UniProt: Q9P2J5)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | initiating methionine |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 123003.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 875.6 | |
| All* | Total formula weight | 123878.9 |
