5OMW
Mutant T252A of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation
Summary for 5OMW
| Entry DOI | 10.2210/pdb5omw/pdb |
| Related | 4aq7 |
| Descriptor | Leucine--tRNA ligase, L-leucyl-tRNA, ZINC ION, ... (5 entities in total) |
| Functional Keywords | reaction catalysed: atp + l-leucine + trna(leu) = amp + diphosphate + l-leucyl-trna(leu) protein translation, aminoacyl-trna activity, leucine-trna ligase, class ia, translation |
| Biological source | Escherichia coli K-12 More |
| Total number of polymer chains | 4 |
| Total formula weight | 256175.67 |
| Authors | Palencia, A.,Cusack, S. (deposition date: 2017-08-02, release date: 2017-11-15, Last modification date: 2024-01-17) |
| Primary citation | Dulic, M.,Cvetesic, N.,Zivkovic, I.,Palencia, A.,Cusack, S.,Bertosa, B.,Gruic-Sovulj, I. Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430:1-16, 2018 Cited by PubMed: 29111343DOI: 10.1016/j.jmb.2017.10.024 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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