4CQN

Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue

Summary for 4CQN

Entry DOI	10.2210/pdb4cqn/pdb
Descriptor	LEUCINE--TRNA LIGASE, ESCHERICHIA COLI TRNA-LEU UAA ISOACCEPTOR, ZINC ION, ... (6 entities in total)
Functional Keywords	ligase-rna complex, ligase, translational fidelity, adaptive response and evolution, ligase/rna
Biological source	ESCHERICHIA COLI K-12 More
Cellular location	Cytoplasm: P07813
Total number of polymer chains	4
Total formula weight	253996.92
Authors	Palencia, A.,Cusack, S.,Cvetesic, N.,Haslaz, I.,Gruic-Sovulj, I. (deposition date: 2014-02-20, release date: 2014-07-02, Last modification date: 2023-12-20)
Primary citation	Cvetesic, N.,Palencia, A.,Halasz, I.,Cusack, S.,Gruic-Sovulj, I. The Physiological Target for Leurs Translational Quality Control is Norvaline Embo J., 33:1639-, 2014 Cited by PubMed: 24935946 DOI: 10.15252/EMBJ.201488199 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation