6KQY

Crystal structure of human leucyl-tRNA synthetase, Leucine-bound form

Summary for 6KQY

Entry DOI	10.2210/pdb6kqy/pdb
Related	6KI4
Descriptor	Leucine--tRNA ligase, cytoplasmic, LEUCINE, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	leucyl-trna synthetase, leucine-bound structure, ligase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	136412.68
Authors	Kim, S.,Son, J.,Kim, S.,Hwang, K.Y. (deposition date: 2019-08-20, release date: 2021-01-27, Last modification date: 2023-11-22)
Primary citation	Kim, S.,Yoon, I.,Son, J.,Park, J.,Kim, K.,Lee, J.H.,Park, S.Y.,Kang, B.S.,Han, J.M.,Hwang, K.Y.,Kim, S. Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35:109031-109031, 2021 Cited by PubMed: 33910001 DOI: 10.1016/j.celrep.2021.109031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation